DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and CG6654

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	704	Identity:	158/704 - (22%)
Similarity:	266/704 - (37%)	Gaps:	152/704 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLATLCRLCLKEHQDAYAIFDEDDTQLSIPVRLMACVA--------LDAKATDTLPKRICQECRY 65
            |:..:|..||.......:|:|....         :|:|        ...:..|.||:::|..|..
  Fly     2 DVDKICLTCLSSTGPLLSIYDGGSG---------SCLADMIREFTKTKPRRNDNLPEKVCLSCLS 57

  Fly    66 QLEKSFLFRQRCQWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDSIAFIEVQDKVRKL 130
            ::...:.|:.:|:.:.:.||:.:        .....::||    .::.....:|..:...:....
  Fly    58 EISNCYTFKIKCENSSRTLRQLL--------PNALPEEPD----SKVSISCPVATTDQAVQTTSW 110

  Fly   131 EDEKWREDFKEEQA----AEMHKRLVKSRLELRAK-------LTTELRKELAEEVRS---EVRKE 181
            |.::.....:.:..    ||.:..|:||.:.:...       ...||..|..|:..|   :|:..
  Fly   111 EPDRCTASVQTDAVTTTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGN 175

  Fly   182 LAEE---VRSQVR-----DDLRNEVSEDIRKEQLAMLLG---ELEV----------------YLT 219
            |.:|   |.:|..     ||  :|:.:.||:..||:..|   |.|:                .||
  Fly   176 LKDEKEVVFTQTNVIYEGDD--HELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLT 238

  Fly   220 EKKAGRWESLDGSEPETKPQVKEDASPSRSKTKALPKRRPSLVDANLKAT---EARKDAKEEEF- 280
            :::..:.::..||:.|.:...||....|..:|    .||..:|..::.||   :|....|:...
  Fly   239 QQENDKHQTPVGSKEEARELEKEQVPQSAKRT----SRRRGVVKQDVPATPPSDAEPSPKQHRLG 299

  Fly   281 --------ILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVH-TDNGEI---YI 333
                    ..|....|:..|     |.....|:............:..|.::| ...|.|   |.
  Fly   300 TQRKLSAPRAGTVNGPSTTS-----GAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYK 359

  Fly   334 INSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVV----FNLGEEISQEQQ 394
            .|.......:.|...|....:|  ::|..|.|   ...:..|.:...:|    .||..:.:..|:
  Fly   360 CNECEKVFVSPDHLAEHQASHG--AHNCPECG---IRCDSKEALSKHMVQGHKRNLRNQCNICQK 419

  Fly   395 VFSFHENVIIVEKEQNDRDEQTPLKRKRSSE---------LVFKQESSCPQPKTGRITDTVKSFQ 450
            ||:....:         ||..    |..:.|         ..|.|.::..|.|. |.::| |||:
  Fly   420 VFTMLSTL---------RDHM----RIHTGEKPFVCNICGKSFTQNANLRQHKL-RHSET-KSFK 469

  Fly   451 CHLCPVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCSE 515
            |.|||.:|.|:..||.|..|| .|.|     ..:|..|..:.:.:.||.:|...|||.:|:.|..
  Fly   470 CELCPHSFVTKAELTSHARTH-TGDK-----PFECEVCLARFTTSCSLAKHKRKHTGERPYACDL 528

  Fly   516 CELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFNH 580
            |.:.|:...|||.|..||||.:.:.||.||..|.|:.:.|.| .|.|.| .|.:.|.:|:..|..
  Fly   529 CPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMH-QRTHQG-ERIYICPVCNEEFKS 591

  Fly   581 VSGLSRHLVTHAGVMFSCKQCGRQFNDRSAVQRHVTTMHKVKNKLTDYISETNE 634
            :..:..||            .|.:.:|:..|  |.|.:...:|.......|.||
  Fly   592 MPEMRSHL------------AGHEQHDKRLV--HFTFLSNKENGSGALEEELNE 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	15/80 (19%)
		vATP-synt_E	109..>244	CDD:304907	34/175 (19%)
		RRF	<161..222	CDD:294170	22/97 (23%)
		zf-C2H2_8	454..530	CDD:292531	26/75 (35%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	10/24 (42%)
		C2H2 Zn finger	513..533	CDD:275368	7/19 (37%)
		zf-H2C2_2	526..550	CDD:290200	12/23 (52%)
		C2H2 Zn finger	541..562	CDD:275368	9/20 (45%)
		C2H2 Zn finger	571..591	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..617	CDD:275368	4/18 (22%)
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071	16/81 (20%)
		C2H2 Zn finger	331..354	CDD:275368	3/22 (14%)
		COG5048	<357..570	CDD:227381	68/238 (29%)
		C2H2 Zn finger	360..380	CDD:275368	3/19 (16%)
		C2H2 Zn finger	385..406	CDD:275370	4/23 (17%)
		C2H2 Zn finger	414..434	CDD:275368	6/32 (19%)
		zf-H2C2_2	427..451	CDD:290200	5/36 (14%)
		C2H2 Zn finger	442..490	CDD:275368	18/49 (37%)
		C2H2 Zn finger	470..487	CDD:275368	8/16 (50%)
		zf-H2C2_2	482..507	CDD:290200	9/30 (30%)
		C2H2 Zn finger	498..518	CDD:275368	5/19 (26%)
		zf-H2C2_2	510..534	CDD:290200	9/23 (39%)
		C2H2 Zn finger	526..546	CDD:275368	7/19 (37%)
		zf-H2C2_2	539..563	CDD:290200	12/23 (52%)
		C2H2 Zn finger	554..574	CDD:275368	9/20 (45%)
		C2H2 Zn finger	582..602	CDD:275368	5/31 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000