DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31365 and ouib

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	75/327 - (22%)
Similarity:	127/327 - (38%)	Gaps:	70/327 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 IDGLELD--EEVPA----------ESGEDFREINMVGSDVVHTDNGEIYIINSASSEDQNQDSTP 348
            |.||.|.  ::||.          .|...||::      .:.|....:.|.:.:||.|::.:...
  Fly    36 ISGLRLVDLDDVPGFMCLCCQAELRSALAFRKL------CIKTQTKWLTIEDDSSSGDEDTNDNS 94

  Fly   349 EFDQDN-GITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGEEISQEQQVFSFHENVIIVEKEQNDR 412
            |.:.:. ..:.:..|::||                  |.||..|           :::|:|..|:
  Fly    95 ELESEKCAFSDFGKKKEGE------------------LVEETFQ-----------VLIEEEPMDK 130

  Fly   413 DEQTPLKRKRSSELVFKQESSCPQPKTGRITDTV--KSFQCHLCPVAFPTQKLLTRHHNTHIKGL 475
            ......|.:...:.:  .|...|..|..:::..:  :.:.|.||.....::....||...| :|.
  Fly   131 TLNRDAKAQLREDGI--DEKCVPSQKIIKVSTKLDDQIYICELCGTHATSKPTFQRHMRKH-RGE 192

  Fly   476 KSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCSECE---LSFSQREVLKRHMDTHTGVK 537
            :     ...|..|..:...|..|:.|..:|||.:||.|..||   :|:..|.:   |..|||..:
  Fly   193 R-----PFGCKDCDARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLI---HERTHTNDR 249

  Fly   538 RHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQCG 602
            .:.|.:|...|.....|:.|: .:|.| .|..:|.:|.|||..    ..|||||...|...:...
  Fly   250 PYVCEECGKKFTTAYVLKNHM-VIHTG-ERNFRCDICDRSFQR----KAHLVTHTRSMMHLQNVK 308

  Fly   603 RQ 604
            :|
  Fly   309 KQ 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	20/78 (26%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	11/27 (41%)
		C2H2 Zn finger	513..533	CDD:275368	6/22 (27%)
		zf-H2C2_2	526..550	CDD:290200	7/23 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	571..591	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..617	CDD:275368	1/7 (14%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	10/47 (21%)
		COG5048	<158..300	CDD:227381	44/156 (28%)
		C2H2 Zn finger	169..189	CDD:275368	5/19 (26%)
		C2H2 Zn finger	197..217	CDD:275368	5/19 (26%)
		zf-H2C2_2	209..234	CDD:290200	10/24 (42%)
		C2H2 Zn finger	225..245	CDD:275368	6/22 (27%)
		zf-H2C2_2	241..262	CDD:290200	7/20 (35%)
		C2H2 Zn finger	253..273	CDD:275368	5/20 (25%)
		zf-H2C2_2	266..288	CDD:290200	8/23 (35%)
		C2H2 Zn finger	281..299	CDD:275368	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050