DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and CG31441

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	105/596 - (17%)
Similarity:	167/596 - (28%)	Gaps:	284/596 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLATLCRLCLKEHQD----AYAIFDEDDTQLSIPVRLMACVALDAKATD-------TLPKRICQE 62
            :|.::||.|.|...:    |..:|::.:...         :::....||       |||..|||.
  Fly     3 ELRSICRTCGKNVTNLQGRATKLFNKSNYHF---------ISILENITDMYLEFDTTLPHLICQC 58

  Fly    63 CRYQLEKSFLFRQRCQWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDSIAFIEVQDKV 127
            |:.||::...||.:|
  Fly    59 CKVQLDRILTFRNKC-------------------------------------------------- 73

  Fly   128 RKLEDEKWREDFKEEQAAEMHKRLVKSRLELRAKLTTELRKELAEEVRSEVRKELAEEVRSQVRD 192
                             .|:||..:.:..:|       |||:..
  Fly    74 -----------------LEVHKSFMAANRKL-------LRKKAI--------------------- 93

  Fly   193 DLRNEVSEDIRKEQLAMLLGELEVYLTEKKAGRWESLDGSEPETKPQVKEDASPSRSKTKALPKR 257
                 |.|::.|..:..|..:|           |:..|           ::...:.:.|..|
  Fly    94 -----VDEELDKPDVEKLQQDL-----------WDHTD-----------QEMCVAMADTAGL--- 128

  Fly   258 RPSLVDANLKATEARKDAKEEEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSD 322
                         .|:|
  Fly   129 -------------LRED------------------------------------------------ 132

  Fly   323 VVHTDNGEIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGE 387
              |.||.:......|:..::||:                 |..::|     .||:|.
  Fly   133 --HNDNEKAKDAEDATQNEKNQE-----------------EQVQVQ-----TEEVEH-------- 165

  Fly   388 EISQEQQVFSFHENVIIVEKEQNDRDEQTPLKRKRSSELVFKQESSCPQPKTGRITDTVKSFQCH 452
              .|||    .| |:.|:.|..:.|   .|.:.||:|                      ||:.|.
  Fly   166 --CQEQ----LH-NMSIISKGVSAR---VPKRTKRNS----------------------KSWFCD 198

  Fly   453 LCPVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCSECE 517
            .|...|.:...|..|...| .|.|     ...|..|..:....:.::||.|:||..:|:.|..|.
  Fly   199 QCGGVFKSSTYLKLHLQRH-SGHK-----PFACDICQAKYYTDNEMRRHRILHTDARPYACRFCS 257

  Fly   518 LSF---SQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFN 579
            .::   |.:.|   |..|||..:..||..|...|...|..|:| ..:|. |.|.:.|.:|.:.|.
  Fly   258 KTYRGCSSKVV---HERTHTNERPFQCQHCDKAFTSTSTRQKH-EMLHT-NQRKYHCEICDQWFL 317

  Fly   580 HVSGLSRHLVT 590
            ..|.|:.|..|
  Fly   318 RSSHLTLHQST 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	20/83 (24%)
		vATP-synt_E	109..>244	CDD:304907	14/134 (10%)
		RRF	<161..222	CDD:294170	8/60 (13%)
		zf-C2H2_8	454..530	CDD:292531	19/78 (24%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	8/27 (30%)
		C2H2 Zn finger	513..533	CDD:275368	5/22 (23%)
		zf-H2C2_2	526..550	CDD:290200	8/23 (35%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	7/20 (35%)
		C2H2 Zn finger	598..617	CDD:275368
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	23/150 (15%)
		COG5048	<174..337	CDD:227381	50/191 (26%)
		C2H2 Zn finger	197..217	CDD:275370	5/19 (26%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		C2H2 Zn finger	253..273	CDD:275368	5/22 (23%)
		zf-H2C2_2	268..290	CDD:290200	9/24 (38%)
		C2H2 Zn finger	281..301	CDD:275368	6/20 (30%)
		C2H2 Zn finger	309..328	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050