DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and zbtb16a

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_955929.1	Gene:	zbtb16a / 323269	ZFINID:	ZDB-GENE-030131-1989	Length:	671	Species:	Danio rerio

Alignment Length:	636	Identity:	127/636 - (19%)
Similarity:	227/636 - (35%)	Gaps:	193/636 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VFSKDPDDYDEDELE---FEDSIAF---IEVQDKVRKLEDEKWREDFKEEQAAEMHKRLVKSRLE 157
            :|.::...|..|.|.   |:..:.:   ..:|.||..|:|..:        |||:        ||
Zfish    62 LFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKVEDLDDLLY--------AAEI--------LE 110

  Fly   158 LRAKLTTELRKELAEEVRSEVRKELAEEVRSQVRDDLRNEVSEDIRKEQLAMLLGELEVYLTEKK 222
            :              |...|...::.|.::|...:|....:::...::.            .|:|
Zfish   111 I--------------EYLEEQCLKILETIQSSDENDTEVNMNDGGTEDD------------EERK 149

  Fly   223 AGRWESLDGSEPETKPQVKE-----------------DASPS---------RSKTKALPKRRPSL 261
            .....:|.||:   |...:|                 |.|||         .|.|||......|:
Zfish   150 GRHGRNLVGSK---KHSTEESGYVSAAQQALALPGMVDQSPSVSTSFGLSTMSPTKAAVDSLMSI 211

  Fly   262 VDANLKATEARKDAKEEEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHT 326
            ..:.|::|.......|:.  |..|:.|. ..::..:.:::||....||.:        ..:.:.:
Zfish   212 GQSLLQSTMHPGVGAEQP--LHGNSHPM-MGEIKTEMMQVDESGEHESPK--------AMESIAS 265

  Fly   327 DNGEIYIINSASSEDQNQDSTPEFDQDNGITS----YNIKEDGEIQFSGEKPEEIEDVVVFNLGE 387
            .|||     .:...|:|:|......:.:.|||    :.::::|    .|::..|:.     .:|.
Zfish   266 SNGE-----RSGEPDKNRDGPGTPTRSSVITSARELHYVRDEG----LGDQQAEVS-----QMGL 316

  Fly   388 EI---SQEQQVFSFHENVIIVEKEQNDRDEQTPLKR----KRSSELVFKQESSC-----PQ---- 436
            |.   ..|:.:.|.:.   |....:|:.....|...    ..|..|....:.|.     ||
Zfish   317 EAMAGMTEKHLASLYG---IPSNHKNEAMLSMPASMASSLHMSPALAMSMDFSAYGGLLPQSFIQ 378

  Fly   437 ----PKTGRITDTVK------SFQCHLCPVAFPTQKLLTRHHNTHIKGLK--------------- 476
                .|.|.:...:|      :.:|::|....|..:.:.:|...| .|:|
Zfish   379 REFFSKLGELAAGIKPDGRSLNERCNVCGAELPDNEAIEQHRKLH-SGMKTYGCELCGKRFLDSL 442

  Fly   477 --------------------------------------SGKGGTLKCPSCALQLSCASSLKRHMI 503
                                                  :|....:.|..|..:....::|::||.
Zfish   443 RLRMHLLSHSAGEKAIVCDQCGAQFQKEDALEAHRQIHTGSDMAIFCLLCGKRFQTQTALQQHME 507

  Fly   504 IHTGLKPFKCSECELSFSQREVLKRHMDTHT-GVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSR 567
            :|.|::.:.||||..:|.....||||:.:|| |....:|..|.|||..:|.|:.| .|:|.| .:
Zfish   508 VHAGVRSYICSECNRTFPSHTALKRHLRSHTAGDHPFECEFCGSCFRDESTLKGH-KRIHTG-EK 570

  Fly   568 THKCHLCHRSFNHVSGLSRHLVTHAGVM-FSCKQCGRQFNDRSAVQRHVTT 617
            .::|:.|.:.|:....|..|...|.|.. |.||.|.::..|.||:.:|:.|
Zfish   571 PYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRT 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907	25/157 (16%)
		RRF	<161..222	CDD:294170	6/60 (10%)
		zf-C2H2_8	454..530	CDD:292531	22/128 (17%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	10/24 (42%)
		C2H2 Zn finger	513..533	CDD:275368	9/19 (47%)
		zf-H2C2_2	526..550	CDD:290200	12/24 (50%)
		C2H2 Zn finger	541..562	CDD:275368	9/20 (45%)
		C2H2 Zn finger	571..591	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..617	CDD:275368	7/18 (39%)
zbtb16a	NP_955929.1	BTB	25..106	CDD:279045	10/51 (20%)
		BTB	35..>106	CDD:197585	10/51 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	130..167		7/51 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..289		10/53 (19%)
		C2H2 Zn finger	403..423	CDD:275368	4/19 (21%)
		C2H2 Zn finger	431..451	CDD:275368	0/19 (0%)
		COG5048	<445..620	CDD:227381	46/176 (26%)
		C2H2 Zn finger	460..480	CDD:275368	0/19 (0%)
		C2H2 Zn finger	489..509	CDD:275368	5/19 (26%)
		zf-C2H2	515..537	CDD:278523	9/21 (43%)
		C2H2 Zn finger	517..537	CDD:275368	9/19 (47%)
		C2H2 Zn finger	546..566	CDD:275368	9/20 (45%)
		zf-H2C2_2	559..582	CDD:290200	7/24 (29%)
		C2H2 Zn finger	574..594	CDD:275368	5/19 (26%)
		zf-H2C2_2	587..608	CDD:290200	8/20 (40%)
		C2H2 Zn finger	602..622	CDD:275368	8/20 (40%)
		C2H2 Zn finger	630..650	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000