DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and Zbtb46

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001101278.1	Gene:	Zbtb46 / 311718	RGDID:	1307408	Length:	601	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	91/400 - (22%)
Similarity:	145/400 - (36%)	Gaps:	92/400 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 VKEDAS----------PSRSKTKALPKRRPSLVDANLKATEARKDAKEEEFILGCNTDPANNS-D 293
            :|.|||          |:.:.|:||           :.|..|.:....   .|...|.|||:| |
  Rat   133 IKSDASDELSEFEIGTPASNSTEAL-----------ISAVMAGRSISP---WLARRTSPANSSGD 183

  Fly   294 VNID---------GLELDEEVPAESGEDFREINMVGSDVVHTDNGEIYIINSASSEDQNQDSTPE 349
            ..|.         |.| |:|..|:..:|....::...||.:   |.:.|.....|......|...
  Rat   184 SAIASCHEGGSSYGKE-DQEPKADGPDDVSSQSLWPGDVGY---GSLRIKEEQISPSHYGGSELS 244

  Fly   350 FDQDNGITSYNIKEDGE---IQFSGEKPEEIEDVVVFNLGEEISQEQQV--------------FS 397
            ..:|..|.: ::.|.|.   .|.:|.:........|.::.:::.::.|.              ||
  Rat   245 SSKDAAIQN-SLSEQGSGDGWQPTGRRKNRKNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFS 308

  Fly   398 FHE-NVIIVEKEQ---NDRDEQTPLKRKRSSELVFKQESSCPQPKTGRITDTVKSFQCHLCPVAF 458
            ..: ||.:...|.   :.|.|:..|......|.:...|:|...|.   :|...:........||.
  Rat   309 SRDSNVDLTVTEASSLDSRGERAELYAHHIDEGLLGGETSYLGPP---LTPEKEEALHQATAVAN 370

  Fly   459 PTQKLLTRHHNTHIKGLKSGKGGTL------------------------KCPSCALQLSCASSLK 499
            ....|::::....:|....|..|:|                        |||.|:........||
  Rat   371 LRAALMSKNSLLSLKADVLGDDGSLLFEYLPKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILK 435

  Fly   500 RHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMG 564
            |||..|||.:|:.|..|...|::||.:|||...|:..|::.|..||..|...::    :|..| |
  Rat   436 RHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAAS----VGIKH-G 495

  Fly   565 NSRTHKCHLC 574
            :.|...|..|
  Rat   496 SRRHGVCADC 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907	1/3 (33%)
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	27/99 (27%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		zf-H2C2_2	497..522	CDD:290200	12/24 (50%)
		C2H2 Zn finger	513..533	CDD:275368	8/19 (42%)
		zf-H2C2_2	526..550	CDD:290200	9/23 (39%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	571..591	CDD:275368	1/3 (33%)
		C2H2 Zn finger	598..617	CDD:275368
Zbtb46	NP_001101278.1	BTB	21..126	CDD:279045
		BTB	32..126	CDD:197585
		COG5048	<362..>487	CDD:227381	34/124 (27%)
		C2H2 Zn finger	421..441	CDD:275368	8/19 (42%)
		zf-H2C2_2	434..458	CDD:290200	12/23 (52%)
		C2H2 Zn finger	449..469	CDD:275368	8/19 (42%)
		zf-H2C2_2	461..484	CDD:290200	8/22 (36%)
		C2H2 Zn finger	477..499	CDD:275368	7/26 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000