DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and Zbtb11

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_038944302.1	Gene:	Zbtb11 / 304010	RGDID:	1308275	Length:	1092	Species:	Rattus norvegicus

Alignment Length:	687	Identity:	150/687 - (21%)
Similarity:	236/687 - (34%)	Gaps:	196/687 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EHQDAYAIFDEDDTQLS-----IPVRLMACVALDAKAT--DTLPKRICQECRYQLEKSFLFRQRC 77
            |.:|..:.|....|..|     .||.....|.:|.|..  .:.||. ||....||.:..|..|.|
  Rat   151 ESEDDLSNFTSPPTTASKTSKKKPVSKHELVFVDTKGVVKRSSPKH-CQAVLKQLNEQRLSNQFC 214

  Fly    78 QWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDSIAFIEVQDKVRKLEDEKWREDFKEE 142
            .         :.||                    :|.|:    .:....|.....|.:|:.|.|:
  Rat   215 D---------VTLL--------------------IEGEE----YKAHKSVLSANSEYFRDLFIEK 246

  Fly   143 QAAEMHKRLV-------KSRLELRAKLTTELRK----------------------ELAEEVRSEV 178
            .|...|:.:|       .|.|.|.....|.:..                      |:.|.|...:
  Rat   247 GAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLM 311

  Fly   179 -RKELAEEVRSQVR-----DDL------------RNEVSEDIRKEQLAMLLGELEVYLTEKKAGR 225
             .|:|....:.:|:     .||            |||.:..:..:     ||..|:.|.
  Rat   312 EEKQLTVYKKGEVQTVASTQDLAAHNGAATPPGPRNEATTTLSSD-----LGHCEIVLL------ 365

  Fly   226 WESLDGSEPETK----------PQVKEDASPSRSKTKALPKRRPSLVDANLKATEARKDAKEEEF 280
               ::|..|||:          |||..:|..|.|....:| ..|:.:.|...|||:.:...|...
  Rat   366 ---VNGEVPETEQNGEPGQQPAPQVSAEAEASVSPAGCIP-NPPTEMGAASLATESNQPELESAV 426

  Fly   281 ILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHTDNGEIYIINSASSEDQNQD 345
            :         ..|..:      ..||.:..|:         :|::|...:..|.|..|.||   .
  Rat   427 V---------REDGGV------ASVPPKISEE---------NVINTSQEDSDIGNDTSPED---T 464

  Fly   346 STPEFDQDNGITSYNIKEDGEIQFSGEKPE--EIEDVVVFNLGEEISQEQQVFSFHENVIIVEKE 408
            .|.:|...:..:...:|::..:..:.||.:  :.:|.....|.:....|......|:.   :||:
  Rat   465 CTKDFSDHSQSSGQPLKDEETLIEATEKTDSGQDDDTYRSRLRQRSVNEGGYIRLHKG---MEKK 526

  Fly   409 QNDRDEQTPLKRKRSSELVFKQESSCPQPKTGR------------------------ITDTVK-- 447
            ...|...:....::.::.:.::.....|||...                        |..|:|
  Rat   527 LQKRKAISKSAVQQVAQKLVQRGKKMKQPKRDAKESAEETPHKCGECGMVFPRRYAFIMHTLKHE 591

  Fly   448 ---SFQCHLCPVAFPTQKLLTRHHNTHIK-----------------GLKSGKGGTLK---CPSCA 489
               .::|.||...|.....|..|...|.:                 |..|.||.|.:   |..|.
  Rat   592 RARDYKCPLCKKQFQYSASLRAHLIRHTRKDAPTSSSSNSTSNEASGASSEKGRTKREFICSICG 656

  Fly   490 LQLSCASSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNL 554
            ..|....||:.||:.|||:||..|..|..:|..:..||.|...|...|:.||..|...|..|.:|
  Rat   657 RTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSL 721

  Fly   555 QQHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTH 591
            |:|:. :|.|.|: :.|.:|.:||:..||||:||..|
  Rat   722 QEHMS-IHTGESK-YFCSVCGKSFHRGSGLSKHLKKH 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871	19/72 (26%)
		vATP-synt_E	109..>244	CDD:304907	36/191 (19%)
		RRF	<161..222	CDD:294170	16/100 (16%)
		zf-C2H2_8	454..530	CDD:292531	27/95 (28%)
		C2H2 Zn finger	485..505	CDD:275368	7/19 (37%)
		zf-H2C2_2	497..522	CDD:290200	12/24 (50%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		zf-H2C2_2	526..550	CDD:290200	9/23 (39%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	571..591	CDD:275368	10/19 (53%)
		C2H2 Zn finger	598..617	CDD:275368
Zbtb11	XP_038944302.1	Integrase_H2C2	68..120	CDD:407771
		BTB_POZ_ZBTB11	195..312	CDD:349511	27/150 (18%)
		PRK12387	<556..621	CDD:183492	11/64 (17%)
		C2H2 Zn finger	570..590	CDD:275368	2/19 (11%)
		C2H2 Zn finger	598..618	CDD:275368	6/19 (32%)
		C2H2 Zn finger	652..672	CDD:275368	7/19 (37%)
		zf-H2C2_2	664..689	CDD:404364	12/24 (50%)
		C2H2 Zn finger	680..700	CDD:275368	6/19 (32%)
		COG5048	695..>801	CDD:227381	25/64 (39%)
		C2H2 Zn finger	708..728	CDD:275368	7/20 (35%)
		C2H2 Zn finger	736..756	CDD:275368	10/19 (53%)
		C2H2 Zn finger	809..827	CDD:275368
		zf-H2C2_2	819..843	CDD:404364
		C2H2 Zn finger	835..855	CDD:275368
		C2H2 Zn finger	863..885	CDD:275368
		C2H2 Zn finger	899..919	CDD:275368
		C2H2 Zn finger	927..947	CDD:275368
		zf-H2C2_2	939..962	CDD:404364
		C2H2 Zn finger	955..976	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000