DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31365 and Hic2

DIOPT Version :9

Sequence 1:NP_732827.1 Gene:CG31365 / 42736 FlyBaseID:FBgn0051365 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001099332.1 Gene:Hic2 / 287940 RGDID:1305338 Length:622 Species:Rattus norvegicus


Alignment Length:426 Identity:91/426 - (21%)
Similarity:142/426 - (33%) Gaps:141/426 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 PETKPQVKED--ASPSRSKTKALP------------------------KRRPSLVDA-------N 265
            ||...|:.:.  .||..:.|.|||                        :...||::.       :
  Rat   266 PEDPAQLSDSQRESPPPTSTSALPVSNSTSYVELGATPDEPMDLEGAEENHLSLLEGQGGQPRKS 330

  Fly   266 LKATEARKDAKEEEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHTDNGE 330
            |:.:..:||..::|.:.|...|......        ....|.|.||       ...|.|  .||.
  Rat   331 LRHSARKKDWNKKEPVAGSPFDRRETGS--------KSSCPGEEGE-------APGDRV--PNGV 378

  Fly   331 IYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGEEISQE--- 392
            :     |||......|.|.:    |...|..||:.|                  .|:::|::   
  Rat   379 L-----ASSAGGGGPSAPSY----GEPPYPCKEEEE------------------NGKDVSEDSGQ 416

  Fly   393 --QQVFSFHENVIIVEKEQNDRDEQTPLKRKRSSELVFKQESSCPQPKTGRITDTVKSFQCHLCP 455
              .:..|.|..                     .:..|::||..    :|....|.:  :.|..|.
  Rat   417 SGSEGGSGHTG---------------------GAHYVYRQEGY----ETVSYGDNL--YVCIPCA 454

  Fly   456 VAFPTQKLLTRHHNTHIK---------GLKSGKGGT---------------------LKCPSCAL 490
            ..||:.:.|..|..||.:         ..::|.||.                     .||..|..
  Rat   455 KGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSTPSSTAYAAEPRPFKCSVCEK 519

  Fly   491 QLSCASSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQ 555
            .....::|::|...|...:||.|:.|...|:||..:.|||.:|.|:|...|.:|...|.::..|.
  Rat   520 TYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLT 584

  Fly   556 QHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTH 591
            :|: |||.| .:.::|.||...|.....|..||..|
  Rat   585 EHM-RVHSG-EKPYECQLCGGKFTQQRNLISHLRMH 618

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31365NP_732827.1 zf-AD 13..86 CDD:214871
vATP-synt_E 109..>244 CDD:304907 3/11 (27%)
RRF <161..222 CDD:294170
zf-C2H2_8 454..530 CDD:292531 24/105 (23%)
C2H2 Zn finger 485..505 CDD:275368 4/19 (21%)
zf-H2C2_2 497..522 CDD:290200 8/24 (33%)
C2H2 Zn finger 513..533 CDD:275368 8/19 (42%)
zf-H2C2_2 526..550 CDD:290200 9/23 (39%)
C2H2 Zn finger 541..562 CDD:275368 6/20 (30%)
C2H2 Zn finger 571..591 CDD:275368 7/19 (37%)
C2H2 Zn finger 598..617 CDD:275368
Hic2NP_001099332.1 BTB_POZ 25..144 CDD:365784
C2H2 Zn finger 450..470 CDD:275368 6/19 (32%)
SUF4-like 510..>559 CDD:411020 14/48 (29%)
C2H2 Zn finger 514..534 CDD:411020 4/19 (21%)
C2H2 Zn finger 514..534 CDD:275368 4/19 (21%)
zf-C2H2 540..562 CDD:395048 9/21 (43%)
C2H2 Zn finger 542..562 CDD:275368 8/19 (42%)
C2H2 Zn finger 542..559 CDD:411020 6/16 (38%)
zf-C2H2 568..590 CDD:395048 6/22 (27%)
C2H2 Zn finger 570..590 CDD:275368 6/20 (30%)
zf-H2C2_2 582..607 CDD:404364 10/26 (38%)
C2H2 Zn finger 598..618 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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