DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and Zbtb7b

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001342135.1	Gene:	Zbtb7b / 22724	MGIID:	102755	Length:	607	Species:	Mus musculus

Alignment Length:	379	Identity:	89/379 - (23%)
Similarity:	136/379 - (35%)	Gaps:	92/379 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 LEVYLTEKKAGRWESLDGSEPETKPQVK-EDASPSRSKTKALPKRRPSLVDANLKATEARKDAKE 277
            ||.:.|.........:...| ::.|||. ....|...:..|...|:|.......|...|.....|
Mouse   226 LEAFATATTTASTSGMPNGE-DSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPE 289

  Fly   278 EEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHTDNGEIYIINSASSEDQ 342
            ...:|   |.|....:..:.| .|.....:..|:.:.......|......|.|::    ...|::
Mouse   290 APTVL---THPLTYEEEEMVG-RLGNSGGSGLGDSYSPPTGAASPAEGPLNYEVF----EGEEEE 346

  Fly   343 NQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEI---EDVVVFNLGEEISQEQQVFSFHENVII 404
            .:.:.|        ..|.:.:..|...|   |||:   ||.:..:|...:|      |.|::.:
Mouse   347 EEMAYP--------PGYGLAQSNEPSLS---PEELGSDEDPIDPDLMAYLS------SLHQDAL- 393

  Fly   405 VEKEQNDRDEQTPLKRKRSSELVFKQESSCPQPKTGRITDTVKSFQCHLCPVAFPTQKLLTRHHN 469
                ....|.|..|.|||.|::        ||
Mouse   394 ----TPGLDGQDKLVRKRRSQM--------PQ--------------------------------- 413

  Fly   470 THIKGLKSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHT 534
                          :||.|...:..|..|.|||..|||.|||.|..|.:.|::.:.||.||..||
Mouse   414 --------------ECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHT 464

  Fly   535 GVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHL 588
            |.:.:.||.|.:.|....:|:.|: .:|.|: |.::|||||::|.....|.|||
Mouse   465 GERPYSCPHCPARFLHSYDLKNHM-HLHTGD-RPYECHLCHKAFAKEDHLQRHL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907	7/30 (23%)
		RRF	<161..222	CDD:294170	3/7 (43%)
		zf-C2H2_8	454..530	CDD:292531	19/75 (25%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		zf-H2C2_2	497..522	CDD:290200	13/24 (54%)
		C2H2 Zn finger	513..533	CDD:275368	7/19 (37%)
		zf-H2C2_2	526..550	CDD:290200	11/23 (48%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	10/18 (56%)
		C2H2 Zn finger	598..617	CDD:275368
Zbtb7b	NP_001342135.1	BTB	87..207	CDD:306997
		COG5048	412..>491	CDD:227381	32/126 (25%)
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		zf-H2C2_2	430..452	CDD:316026	12/21 (57%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		C2H2 Zn finger	471..491	CDD:275368	6/20 (30%)
		zf-H2C2_2	483..508	CDD:316026	11/26 (42%)
		C2H2 Zn finger	499..517	CDD:275368	10/18 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000