DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and ZBTB7C

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_016881094.1	Gene:	ZBTB7C / 201501	HGNCID:	31700	Length:	668	Species:	Homo sapiens

Alignment Length:	377	Identity:	82/377 - (21%)
Similarity:	136/377 - (36%)	Gaps:	125/377 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 DNGEIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGEEISQ 391
            |.||         ||..:|...:.|.|:        |:.|.:...|:.::.:|...|...|.:..
Human   181 DGGE---------EDDKEDDDDDEDDDD--------EEDEEEEEEEEEDDDDDTEDFADQENLPD 228

  Fly   392 EQQVFSFHENVI----IVEKEQNDRDEQTP------------LKRKRSSELVFKQ----ESSCPQ 436
            .|.: |.|::..    :.||..:|.....|            :.|..|.|.:.::    :::.|.
Human   229 PQDI-SCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKANIPD 292

  Fly   437 PKTGRITDTVKSFQCHLCPVAF------PTQ-------KLLTRHHN------------------- 469
            .:.. ::.....|..||.|..|      |.|       .|:.::..
Human   293 RRPS-LSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPPPPPPFPN 356

  Fly   470 ---------------------------------THIKGL----------KSGKGGTLKCPSCALQ 491
                                             ||:.||          |.....:.:||.|...
Human   357 DFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKPKASQQCPICHKV 421

  Fly   492 LSCASSLKRHMIIHTGLKPFKCSECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQ 556
            :..|..|.|||..|||.||:.|:.||:.|::::.||.||..|||.:.:.|..|::.|....:|:.
Human   422 IMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKN 486

  Fly   557 HIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQC----GRQ 604
            |: |:|.| .|.::|..|::||.....|.||:...     ||:..    ||:
Human   487 HM-RIHTG-VRPYQCEFCYKSFTRSDHLHRHIKRQ-----SCRMARPRRGRK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	29/150 (19%)
		C2H2 Zn finger	485..505	CDD:275368	8/19 (42%)
		zf-H2C2_2	497..522	CDD:290200	13/24 (54%)
		C2H2 Zn finger	513..533	CDD:275368	8/19 (42%)
		zf-H2C2_2	526..550	CDD:290200	10/23 (43%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..617	CDD:275368	3/11 (27%)
ZBTB7C	XP_016881094.1	BTB	73..176	CDD:279045
		BTB	84..177	CDD:197585
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		zf-H2C2_2	430..452	CDD:290200	12/21 (57%)
		C2H2 Zn finger	443..463	CDD:275368	8/19 (42%)
		zf-H2C2_2	456..480	CDD:290200	10/23 (43%)
		C2H2 Zn finger	471..491	CDD:275368	6/20 (30%)
		zf-H2C2_2	483..508	CDD:290200	10/26 (38%)
		C2H2 Zn finger	499..517	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000