DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31365 and unc-98

DIOPT Version :9

Sequence 1:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_509284.2	Gene:	unc-98 / 181020	WormBaseID:	WBGene00006827	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	370	Identity:	76/370 - (20%)
Similarity:	116/370 - (31%)	Gaps:	117/370 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 EARKDAKE-EEFILGCNTDPANNSDVNIDGLELDEEVPAESGEDFREINMVGSDVVHTDNGEIYI 333
            ||||:..: ||.:..|                           |..::::..:::||  ..|.:.
Worm     8 EARKERDDFEELMNAC---------------------------DLAKMSVKNNEMVH--GLETFG 43

  Fly   334 INSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVVVFNLGEEISQEQQVFSF 398
            ||..|||:.|:                           |||:||..||
Worm    44 INGESSENGNK---------------------------EKPKEIMKVV----------------- 64

  Fly   399 HENVIIVEKEQNDRDEQTPLKRK-----RSSELVFKQESSCPQPKTGRITDTVKSFQCHLCPVAF 458
               ...||........|||.|..     .|.:...:|:.:..|.......    .::|..|.:.|
Worm    65 ---APTVEAYVGSSSAQTPTKSSGGALDGSDQQEVRQDGTSVQKDDNGFV----FYKCRFCGLTF 122

  Fly   459 PTQKLLTRHHNTHIKGLKSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKCSEC-ELSFSQ 522
            .....|..|...|      .......|..|......|..|:.|...|:.:..:|| || ...||.
Worm   123 NFMNTLRAHERIH------DVSQPYVCGKCGDSFEFACQLEYHAAQHSEIDGYKC-ECGRTFFSY 180

  Fly   523 REVL-KRHMD----------THT---------GVKRHQCPQCSSCFAQKSNLQQHIGRVHMG-NS 566
            .|:| .:|.|          |.|         .|.....||  ..|..:....:|..||:.. .|
Worm   181 TEMLYHKHTDDPLELIGAPETTTIKVSKKRVLPVSEQDLPQ--PAFVTEGYEPKHPLRVYNDVRS 243

  Fly   567 RTHKCHLCHRSFNHVSGLSRHLVTHAGVMFSCKQCGRQFNDRSAV 611
            :.:.|..|.:|::...||:.|:.:|.|..:...:..|....|..|
Worm   244 KPYICEYCSKSYSDSRGLAYHMYSHRGEKYFNPRASRYMMGREGV 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	19/77 (25%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	8/25 (32%)
		C2H2 Zn finger	513..533	CDD:275368	9/31 (29%)
		zf-H2C2_2	526..550	CDD:290200	9/43 (21%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	571..591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..617	CDD:275368	3/14 (21%)
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	5/19 (26%)
		C2H2 Zn finger	143..163	CDD:275368	5/19 (26%)
		SFP1	<169..268	CDD:227516	26/101 (26%)
		C2H2 Zn finger	171..189	CDD:275368	7/18 (39%)
		C2H2 Zn finger	248..268	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000