| Sequence 1: | NP_524458.1 | Gene: | CenB1A / 42735 | FlyBaseID: | FBgn0039056 | Length: | 828 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476510.1 | Gene: | GIT2 / 9815 | HGNCID: | 4273 | Length: | 759 | Species: | Homo sapiens |
| Alignment Length: | 528 | Identity: | 110/528 - (20%) |
|---|---|---|---|
| Similarity: | 191/528 - (36%) | Gaps: | 148/528 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 389 KIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMMELG 453
Fly 454 NEVVNRIYEARIGDDC----GLKKPTEQCEIGVREA-WIKAKYVERRFVCGMP------------ 501
Fly 502 -----------------------------KPQE-----LLASETAEVLSIDSGGV--VEDGESGG 530
Fly 531 SGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKTLSDDPSIYNTAKTGDELEDDDDDESINIPSM 595
Fly 596 ---SLSIS------RDDLLVIG----DDLALDRLETPGILGSDQESTDGESDAESPEELPFSQLD 647
Fly 648 ANQLLYMASVVHNLPVMCMAFALGADKMWKNP-------QDRQRSFLHQAVISGSVMACEFLLLN 705
Fly 706 GAAIDAVD-----EMGYSALHISTAKGHIAQVYLLLKHKAAYDLSSSDGKKALDIAVDQENADIV 765
Fly 766 TLLRLTQLNDEIGPNDEYNGEDETYKNVMKDFSKLPASQTRVLRQRHDSN--------------T 816
Fly 817 LESQRSSL 824 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CenB1A | NP_524458.1 | BAR_ACAPs | 18..217 | CDD:153287 | |
| PH | 259..352 | CDD:278594 | |||
| PH_ACAP | 260..355 | CDD:270070 | |||
| ArfGap | 384..497 | CDD:279720 | 40/112 (36%) | ||
| ANK | 652..768 | CDD:238125 | 25/127 (20%) | ||
| Ank_4 | 683..736 | CDD:290365 | 11/57 (19%) | ||
| ANK repeat | 687..713 | CDD:293786 | 6/25 (24%) | ||
| ANK repeat | 715..746 | CDD:293786 | 4/30 (13%) | ||
| GIT2 | NP_476510.1 | ArfGap | 2..124 | CDD:214518 | 43/119 (36%) |
| ANK | 109..220 | CDD:238125 | 17/117 (15%) | ||
| ANK 1 | 132..161 | 0/28 (0%) | |||
| Ank_2 | 137..229 | CDD:289560 | 13/98 (13%) | ||
| ANK repeat | 137..165 | CDD:293786 | 0/27 (0%) | ||
| ANK 2 | 166..195 | 4/28 (14%) | |||
| ANK repeat | 167..197 | CDD:293786 | 5/29 (17%) | ||
| ANK 3 | 199..228 | 7/35 (20%) | |||
| GIT_SHD | 266..294 | CDD:285690 | 6/41 (15%) | ||
| GIT_SHD | 330..358 | CDD:285690 | 8/38 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 379..422 | 7/45 (16%) | |||
| GIT_CC | 414..478 | CDD:293167 | 11/62 (18%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 480..538 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 554..643 | ||||
| GIT1_C | 638..752 | CDD:289013 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||