DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenB1A and GTS1

DIOPT Version :9

Sequence 1:	NP_524458.1	Gene:	CenB1A / 42735	FlyBaseID:	FBgn0039056	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_011334.1	Gene:	GTS1 / 852694	SGDID:	S000003149	Length:	396	Species:	Saccharomyces cerevisiae

Alignment Length:	159	Identity:	45/159 - (28%)
Similarity:	72/159 - (45%)	Gaps:	38/159 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 EEFLKIPGNA-YCCDCRSPEPRWASINLGITLCIECSGVHRSL-GVH----YSKVRSLTLDAWES 443
            :|.:....|| .|.:|.:..|.|.|:|||:.||..|:.|||.: |..    :|.|:||::|.|..
Yeast    18 KELINSSENANKCGECGNFYPTWCSVNLGVFLCGRCASVHRKVFGSRDDDAFSNVKSLSMDRWTR 82

  Fly   444 ENVKVMMELGNEVVN-RIYEAR------IGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVCGMP 501
            |::..::.||....| |.:..:      .|||          :..:.|.:|:.||:..:|.....
Yeast    83 EDIDELVSLGGNKGNARFWNPKNVPFPFDGDD----------DKAIVEHYIRDKYILGKFRYDEI 137

  Fly   502 KPQELLASETAEVLSIDSGGVVE--DGES 528
            ||:             |.|..::  ||||
Yeast   138 KPE-------------DFGSRMDDFDGES 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287
		PH	259..352	CDD:278594
		PH_ACAP	260..355	CDD:270070
		ArfGap	384..497	CDD:279720	36/124 (29%)
		ANK	652..768	CDD:238125
		Ank_4	683..736	CDD:290365
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
GTS1	NP_011334.1	COG5347	8..310	CDD:227651	45/159 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810