DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenB1A and AGAP9

DIOPT Version :9

Sequence 1:NP_524458.1 Gene:CenB1A / 42735 FlyBaseID:FBgn0039056 Length:828 Species:Drosophila melanogaster
Sequence 2:NP_001177739.1 Gene:AGAP9 / 642517 HGNCID:23463 Length:658 Species:Homo sapiens


Alignment Length:353 Identity:99/353 - (28%)
Similarity:151/353 - (42%) Gaps:97/353 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 EGYLFKKKSKGFKTWCRRWFYLSDNQLV--------YRKRSNEDSFSVMEEDLRICSVR------ 311
            :|.|.|:..|..|||.:::..|..|.::        |.|..::     .|.|||..:::      
Human   286 QGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHK-----KEIDLRTSTIKVPGKWP 345

  Fly   312 --------PVNE--------------GDRRFCFEV-ISPT---------------KSHI------ 332
                    |::.              || ..||.. ||.|               |.|:      
Human   346 SLATSACAPISSSKSNGLSKDMDTGLGD-SICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTN 409

  Fly   333 -------------LQADSADMLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPAKRRIHW 384
                         .:|.:.:....|:.|:|..|.|::|...:..|:.|.|:       ....:..
Human   410 NFMIVSATGQTWHFEATTYEERDAWVQAIQSQILA
SLQSCKSSKSKSQLTS-------QSEAMAL 467

  Fly   385 EEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVM 449
            :....:.|||:|.||.:..|:|||:|||:.:||||||:|||.|...|:||||.||.|..|..|||
Human   468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVM 532

  Fly   450 MELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVCGMP-----KPQELLAS 509
            ..:|||:.|.|:|   |...|..||:.:.....:|.||::||.|:.|:..:|     ..|:||.:
Human   533 SSIGNELANSIWE---GSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRA 594

  Fly   510 ETAE-----VLSIDSGGVVEDGESGGSG 532
            .|.|     :|.:..|...|..|:.|.|
Human   595 TTDEDLQTAILLLAHGSREEVNETCGEG 622

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenB1ANP_524458.1 BAR_ACAPs 18..217 CDD:153287
PH 259..352 CDD:278594 29/161 (18%)
PH_ACAP 260..355 CDD:270070 30/164 (18%)
ArfGap 384..497 CDD:279720 51/112 (46%)
ANK 652..768 CDD:238125
Ank_4 683..736 CDD:290365
ANK repeat 687..713 CDD:293786
ANK repeat 715..746 CDD:293786
AGAP9NP_001177739.1 PH_AGAP 280..444 CDD:241281 30/163 (18%)
PH 283..442 CDD:278594 29/161 (18%)
ArfGap 466..580 CDD:279720 52/116 (45%)
ANK repeat 591..621 CDD:293786 8/29 (28%)
Ank_2 <596..643 CDD:289560 8/27 (30%)
Ank 623..>643 CDD:278452 99/353 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D751525at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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