DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenB1A and AGAP9

DIOPT Version :10

Sequence 1:NP_524458.1 Gene:CenB1A / 42735 FlyBaseID:FBgn0039056 Length:828 Species:Drosophila melanogaster
Sequence 2:NP_001177739.1 Gene:AGAP9 / 642517 HGNCID:23463 Length:658 Species:Homo sapiens


Alignment Length:353 Identity:99/353 - (28%)
Similarity:151/353 - (42%) Gaps:97/353 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 EGYLFKKKSKGFKTWCRRWFYLSDNQLV--------YRKRSNEDSFSVMEEDLRICSVR------ 311
            :|.|.|:..|..|||.:::..|..|.::        |.|..::     .|.|||..:::      
Human   286 QGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHK-----KEIDLRTSTIKVPGKWP 345

  Fly   312 --------PVNE--------------GDRRFCFEV-ISPT---------------KSHI------ 332
                    |::.              || ..||.. ||.|               |.|:      
Human   346 SLATSACAPISSSKSNGLSKDMDTGLGD-SICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTN 409

  Fly   333 -------------LQADSADMLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPAKRRIHW 384
                         .:|.:.:....|:.|:|..|.|::|...:..|:.|.|:       ....:..
Human   410 NFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTS-------QSEAMAL 467

  Fly   385 EEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVM 449
            :....:.|||:|.||.:..|:|||:|||:.:||||||:|||.|...|:||||.||.|..|..|||
Human   468 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVM 532

  Fly   450 MELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVCGMP-----KPQELLAS 509
            ..:|||:.|.|:|   |...|..||:.:.....:|.||::||.|:.|:..:|     ..|:||.:
Human   533 SSIGNELANSIWE---GSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRA 594

  Fly   510 ETAE-----VLSIDSGGVVEDGESGGSG 532
            .|.|     :|.:..|...|..|:.|.|
Human   595 TTDEDLQTAILLLAHGSREEVNETCGEG 622

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenB1ANP_524458.1 BAR_ACAPs 18..217 CDD:153287
PH_ACAP 260..355 CDD:270070 30/164 (18%)
ArfGap_ACAP 381..497 CDD:350064 51/115 (44%)
ANKYR <647..>768 CDD:440430
ANK repeat 687..713 CDD:293786
ANK repeat 715..746 CDD:293786
AGAP9NP_001177739.1 PH_AGAP 280..444 CDD:241281 30/163 (18%)
ArfGap_AGAP2 464..572 CDD:350078 49/110 (45%)
ANKYR <591..>643 CDD:440430 10/32 (31%)
ANK repeat 591..621 CDD:293786 8/29 (28%)
Blue background indicates that the domain is not in the aligned region.

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