Protein Alignment CenB1A and appl1

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_021335332.2
• Gene: appl1 / 571540
• ZFINID: ZDB-GENE-081016-1
• Length: 708
• Species: Danio rerio
• Alignment Length: 448
• Identity: 101/448 - (22%)
• Similarity: 186/448 - (41%)
• Gaps: 53/448 - (11%)

  Fly     5 IEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDLQ-Q 68
            :..||.|:|||:.|..:...|.|...:.....::.|......|:..|........:..|.|.: |
Zfish     7 LPIEETLEDSPQTRSLLGVFEEDAAAISSYFSQLFKAMQRIYDAQNELSAATHLTSKLLKDYEKQ 71

  Fly    69 HFL---DNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKGHFLKV 130
            .|.   |::...:.|.:......|::..|.:|..|.:..::..::.|.:.|:.::...|..|...
Zfish    72 RFPLGGDDEVMSSTLQQFAKVIDELSSCHAVLSTQLADAMMFPITQFQERDLREILILKEVFQLA 136

  Fly   131 SEGYDNALIKNAQASKNRPQE--MQEAANILSASKSCFQHTALDYVNYITLAQARKVPSILSTLL 193
            |:.:|.|:.:.::.||.:..|  ..|....:..|:.....|.:.|...:.:.|.:|..::|..||
Zfish   137 SDDHDAAVHRYSRLSKRKENEKVKNEVMEDVYTSRKKQHETTMHYFASLNMLQYKKKIALLEPLL 201

  Fly   194 DYYQACVTYYHQGFD-LCNDFDEFFKNISEDLNALR----GDYQQLEKAMQN-RHMSVNRYC--- 249
            .|.||.::::..|.: |...:::|..||...:..:|    .|.:.:|:.:|: :.:|...|.
Zfish   202 GYMQAQISFFKLGSENLTQQWEDFLTNIGTSVQNVRREMDSDAEAMEQTIQDLKEVSDPLYMPDP 266

  Fly   250 DSN---TNSTSNKIEGYLFKKKSKGF--KTWCRRWFYLSDNQLVYRKRSNEDSFSVMEEDLRICS 309
            |.|   .|....:..|||..:...|.  .:|.|::|:.....|:.:.|.......||  |:..||
Zfish   267 DPNRIPVNRNLTRKAGYLNTRNKTGLVSSSWERQYFFTQGGNLMSQSRGAVAGGLVM--DIDNCS 329

  Fly   310 VRPVNEGDRRFCFEV--ISPTKSHILQADSADMLSLWISALQH------------SIGAAIQHDS 360
            |..|:..||||||::  ....|:.:|||||......||:.:.:            .|.|.:...:
Zfish   330 VMAVDCEDRRFCFQITAFDGKKAAVLQADSRKDCEEWIATINNISKRIYLSENPEEIAARVNQSA 394

  Fly   361 THHSRPQSTNAPNNSLPAKRRIHWEEF-------LKIPGNAYCCDCRSPEPRWASINL 411
            .....|.         |:.::.| |.|       :|...:...|...|..|..:|::|
Zfish   395 LEAVTPS---------PSFQQRH-ESFRPNTQGKVKASRSGSQCSVGSESPALSSLSL 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	40/205 (20%)
		PH_ACAP	260..355	CDD:270070	31/110 (28%)
		ArfGap_ACAP	381..497	CDD:350064	9/38 (24%)
		ANKYR	<647..>768	CDD:440430
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
appl1	XP_021335332.2	None