Protein Alignment CenB1A and acap1

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_073762908.1
• Gene: acap1 / 561771
• ZFINID: ZDB-GENE-070112-1242
• Length: 788
• Species: Danio rerio
• Alignment Length: 833
• Identity: 295/833 - (35%)
• Similarity: 437/833 - (52%)
• Gaps: 115/833 - (13%)

  Fly     2 RATIEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDL 66
            |.|:   ||..:       :.|.|.::..||.||||::|.|:..:::|:.|.:|..:|...|.:|
Zfish    43 RTTL---ECKSE-------IEKVEVNVSELETRLEKLVKQCHTMLETGRAYCQNSKSFVNGLKEL 97

  Fly    67 QQHFLDNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKGHFLKVS 131
            ..|..::::..:.|.|.......:......|::...:.|...|..|||||:.:.||.:..|.:.|
Zfish    98 GHHCSEDRSMGDCLEKFSKKLSAIVSAQEELIETTQKDVKLKLQNFVKDDVKRFKDVRKEFERSS 162

  Fly   132 EGYDNALIKNAQASKNRPQEMQEAANILSASKSCFQHTALDYVNYITLAQARKVPSILSTLLDYY 196
            |..:.||.:||||.:.:..|::||:|.|..::..|:..|||||..|.:.::||...||..:|...
Zfish   163 ENLEAALSRNAQAPRGKQHEVEEASNNLLIARRAFRSGALDYVLQINVIESRKKTEILQAMLSLI 227

  Fly   197 QACVTYYHQGFDLCNDFDEFFKNISED-----LNALRGDYQQLEKAMQNRHMSVNR----YCDSN 252
            ||...::.|......:.:.:.|.:.::     ||:.|.     ::.|:.||.:|.:    |.||.
Zfish   228 QAQALFFQQSHQSLAELENYRKELHDENAQLVLNSARD-----KRDMEQRHGAVKKKDVSYDDSI 287

  Fly   253 TNSTSN-----KIEGYLFKKKSKGFKTWCRRWFYLSDNQLVYRKRSNEDSFSVMEEDLRICSVRP 312
            .:.:.:     .:||||:|:.|..||||.||||.:..|||||:|:.|| ..:|:.||||:|:|:|
Zfish   288 MDFSPDAPNGIAMEGYLYKRASNAFKTWSRRWFSIQKNQLVYQKKHNE-QITVVVEDLRLCTVKP 351

  Fly   313 VNEGDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQ--HDSTHHSRPQSTNAPNNS 375
            .:|.||||||||:||:||.:|||||......||||:|:||.:|.|  .|..|.||.:.::....|
Zfish   352 CSEQDRRFCFEVVSPSKSCLLQADSERQQQSWISAVQNSIASAFQERRDDNHSSRDRCSSVSVGS 416

  Fly   376 L-------PAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKV 433
            :       .|..|...||...|.||:.||||..|.|.||||||||||||.|||:|||||||:|||
Zfish   417 VRLSGGEPEACVREALEEVQAISGNSQCCDCGEPGPDWASINLGITLCITCSGIHRSLGVHFSKV 481

  Fly   434 RSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVC 498
            ||||||:||.|.||:|.||||..:|:|||||| ::..:|||........:|:||::||||::|:.
Zfish   482 RSLTLDSWEPELVKLMCELGNTAINKIYEARI-EEITIKKPHPSSPRQDKESWIRSKYVEKKFIH 545

  Fly   499 GMPKPQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPK 563
            .:|                         |:|...|                  |||...:|:...
Zfish   546 KLP-------------------------ETGRGQI------------------LRRSSARRNRST 567

  Fly   564 TLSDDPSIYNTAKTGDELEDDDDDESINIPSMSLSISRDDLLVIGDDLALDRLETPGILGSDQES 628
            |                     :|:....|::.....|         :.|.||  .|:..||...
Zfish   568 T---------------------EDKPCTRPALKPKPGR---------VTLPRL--TGLTPSDIMK 600

  Fly   629 TDGESDAESPEELPFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQDRQRSFLHQAVIS 693
            .:..|..::.||...|.|....|||.::.:.:.|:|..|.|.|||..|.|..:..::.|.||||:
Zfish   601 NNSGSHKDNNEEEDLSGLHPGALLYRSASMQHFPLMADALAHGADVNWVNVAEDSKTPLIQAVIA 665

  Fly   694 GSVMACEFLLLNGAAIDAVDEMGYSALHISTAKGHIAQVYLLLKHKAAYDLSSSDGKKALDIAVD 758
            .|:.||||||.|||.::.||..|...||.:|..||...|.|.||..|.|:....:.|..:.||:|
Zfish   666 NSLAACEFLLQNGANVNQVDSNGRGPLHHATILGHTGLVCLFLKRGADYNAKDIEEKDPIGIAID 730

  Fly   759 QENADIVTLLRLTQLNDEIGPNDEYNGEDETYKNVMKDFSKLPASQTRVLRQR 811
            ..|||||||||:.::|.|:...|.....|:||.::.:|||::.::....|::|
Zfish   731 NANADIVTLLRIAKMNKEMREMDGTPSGDDTYHDIFRDFSQMASNNPEKLKRR 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	58/198 (29%)
		PH_ACAP	260..355	CDD:270070	55/94 (59%)
		ArfGap_ACAP	381..497	CDD:350064	70/115 (61%)
		ANKYR	<647..>768	CDD:440430	51/120 (43%)
		ANK repeat	687..713	CDD:293786	15/25 (60%)
		ANK repeat	715..746	CDD:293786	12/30 (40%)
acap1	XP_073762908.1	None