Protein Alignment CenB1A and asap2b

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_073788830.1
• Gene: asap2b / 560581
• ZFINID: ZDB-GENE-030131-5060
• Length: 1061
• Species: Danio rerio
• Alignment Length: 805
• Identity: 165/805 - (20%)
• Similarity: 295/805 - (36%)
• Gaps: 224/805 - (27%)

  Fly    23 KEESDIEH-LEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDLQQHFLDN------------- 73
            :|..|::. :..:::|.:|..|   .||:.:|:|:..:..::    :.|.||
Zfish    78 EEALDLDRSVLHKMKKSVKAIN---SSGQTHVENEEQYIQAI----ERFTDNTVYKDDPEMSNYF 135

  Fly    74 ------KNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVK-DYKGHFLKVS 131
                  .....||.|  :..|.||...|..||.           .:|.|:..|| |.|..|.|..
Zfish   136 LTFAGFTKELTALFK--NLLQNMNNIITFPLDS-----------LLKGDLKGVKGDLKKPFDKAW 187

  Fly   132 EGYDNALIKNAQASKNRPQEM---------QEAANILSASKSCFQHTALDYVNYITLAQARKVPS 187
            :.|:..|.|..:..:...::.         .|.|..:...:..||....:|:..:...:.:|...
Zfish   188 KDYETKLSKIEKEKREHAKQHGLIRTEISGGEIAEEMEKERRLFQLQMCEYLIKVNEIKVKKGVD 252

  Fly   188 ILSTLLDYYQACVTYYHQGFDLCNDFDEFFKNISEDLNALR----GDYQQLEKAMQNRHMSVNRY 248
            :|..|:.|:.|...::..|..:.::...|.:.::.||.|.:    .:.:||.:..:....::...
Zfish   253 LLHNLIKYFHAQCNFFQDGLKVVDNLKPFMEKLATDLTANKQTQDAERKQLLQLKETLKSALQSE 317

  Fly   249 CDSNTNSTSNKIEGY-----------------LFKKKSKGF-KTWCRRWFYLSDNQL-VYRKRSN 294
            |..:..|..|  .||                 :..|:|:|. |.|.:|...:.:..| :.....|
Zfish   318 CKEDAQSKQN--AGYSLHQLQGNKAHGTERSGMLLKRSEGLRKVWQKRKCSVKNGLLTISHGTPN 380

  Fly   295 EDSFSVMEEDLRICSVRPVNEGDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQHD 359
            ....::   :|..|.|:  ...|.:.||::||..:::..|.:......:|:|.||:|...|:
Zfish   381 APPANL---NLLTCQVK--RNPDEKKCFDLISHDRTYHFQTEDEAECQVWVSVLQNSKEEAL--- 437

  Fly   360 STHHSRPQSTNAPNNSLPAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHR 424
             .:..:.......||.:....:....|..|:.||..||||.:..|.|.|.|||:.:||||||:||
Zfish   438 -NNAFKDDQNEGENNIVRELTKAIVGEVKKMSGNDVCCDCGASNPTWLSTNLGVLICIECSGIHR 501

  Fly   425 SLGVHYSKVRSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKA 489
            .:|||||:::|||||...:..:.:...:||...|.|.||::..:  :.||....::.||:.:|.|
Zfish   502 EMGVHYSRIQSLTLDLLGTSELLLANSVGNAAFNEIMEAKLSSE--IPKPNPSSDMQVRKDFITA 564

  Fly   490 KYVERRFVCGMPKPQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRR 554
            ||.|:||                                              ..:|:|
Zfish   565 KYTEKRF----------------------------------------------AQKKYA------ 577

  Fly   555 RQKQRSIPKTLSDDPSIYNTAKTGDELEDDDDDESINIPSMSLSISRDDLLVIGDDLA--LDRLE 617
                                            |.:..:.:|..::...|:..:....|  ||.:|
Zfish   578 --------------------------------DNAARLHAMCDAVKSRDIFSLIQVYAEGLDLME 610

  Fly   618 TPGILGSDQESTDGESDAESPEELPFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQDR 682
            |   :....:...||:..    .|....:|.|
Zfish   611 T---INQPNQHEPGETSL----HLAVRMVDRN--------------------------------- 635

  Fly   683 QRSFLHQAVISGSVMACEFLLLNGAAIDAVDEMGYSALHISTAKGHIAQVYLLLKHKAAYDLSSS 747
                        |:...:||:.|...:|.....|.:|||......:...:.|||:.||:..:::.
Zfish   636 ------------SLHIVDFLVQNSGNLDKQTAKGSTALHYCCLTDNSECMKLLLRGKASVSITND 688

  Fly   748 DGKKALDIAVDQENADIVTLLRLTQ 772
            .|:.|||:|...:::....||...|
Zfish   689 AGETALDLAQRLKHSKCEELLTQAQ 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	43/223 (19%)
		PH_ACAP	260..355	CDD:270070	24/113 (21%)
		ArfGap_ACAP	381..497	CDD:350064	48/115 (42%)
		ANKYR	<647..>768	CDD:440430	21/120 (18%)
		ANK repeat	687..713	CDD:293786	5/25 (20%)
		ANK repeat	715..746	CDD:293786	9/30 (30%)
asap2b	XP_073788830.1	None