DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenB1A and ARFGAP1

DIOPT Version :9

Sequence 1:NP_524458.1 Gene:CenB1A / 42735 FlyBaseID:FBgn0039056 Length:828 Species:Drosophila melanogaster
Sequence 2:XP_011527203.1 Gene:ARFGAP1 / 55738 HGNCID:15852 Length:416 Species:Homo sapiens


Alignment Length:207 Identity:50/207 - (24%)
Similarity:80/207 - (38%) Gaps:67/207 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   393 NAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMMELGNEVV 457
            |..|.:|.:..|:|.|:..||.:|:||||.||.||||.|.|||:|:|.|:...::.|...||...
Human    19 NNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKF 83

  Fly   458 NRIYEARIG-DDCGLKKPTEQCEIGVREAW-IKAKYVERRFVCGMPKPQELLASETAEVLSIDSG 520
            ....|::.. |.|                | ::.||                             
Human    84 REFLESQEDYDPC----------------WSLQEKY----------------------------- 103

  Fly   521 GVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKTLSDDPSIYN---------TAK 576
                  .|..:.:.:...::|...|:|:::....:......|:||   ||:.:         ||.
Human   104 ------NSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTL---PSMVHRVSGQPQSVTAS 159

  Fly   577 TGDELED--DDD 586
            :....||  :||
Human   160 SDKAFEDWLNDD 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenB1ANP_524458.1 BAR_ACAPs 18..217 CDD:153287
PH 259..352 CDD:278594
PH_ACAP 260..355 CDD:270070
ArfGap 384..497 CDD:279720 35/105 (33%)
ANK 652..768 CDD:238125
Ank_4 683..736 CDD:290365
ANK repeat 687..713 CDD:293786
ANK repeat 715..746 CDD:293786
ARFGAP1XP_011527203.1 ArfGap 7..114 CDD:279720 36/145 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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