DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenB1A and Agap1

DIOPT Version :9

Sequence 1:NP_524458.1 Gene:CenB1A / 42735 FlyBaseID:FBgn0039056 Length:828 Species:Drosophila melanogaster
Sequence 2:NP_835220.1 Gene:Agap1 / 347722 MGIID:2653690 Length:857 Species:Mus musculus


Alignment Length:274 Identity:85/274 - (31%)
Similarity:135/274 - (49%) Gaps:47/274 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   285 NQLVYRKRSNEDSFSV---------MEEDLRICSVRPVNEGDRRFCFEVISPT-KSHILQADSAD 339
            |:..:|::.:..:|..         .||:|.               |.::|.| ::...:|.:.:
Mouse   525 NRKKHRRKKSTSNFKADGLSGTAEEQEENLE---------------FIIVSLTGQTWHFEATTYE 574

  Fly   340 MLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPAKRRIHWEEFLKIPGNAYCCDCRSPEP 404
            ....|:.|::..|.|::|  |...|:.:|.....:...|.:.|.     .:.||::|.||.:..|
Mouse   575 ERDAWVQAIESQILASLQ
--SCESSKNKSRLTSQSEAMALQSIR-----NMRGNSHCVDCDTQNP 632

  Fly   405 RWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDC 469
            .|||:|||..:||||||:||:||.|.|:||||.||.|..|.:|||..:|||:.|.::|.  |.. 
Mouse   633 NWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEE--GSQ- 694

  Fly   470 GLKKPTEQCEIGVREAWIKAKYVERRFVCGMP-----KPQELLASETAE------VLSIDSGGVV 523
            |..||:.......:|.||:|||.::.|:..:|     ..|:||.: |||      :|.:..|...
Mouse   695 GRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCTEFSLGQQLLRA-TAEEDLRTVILLLAHGSRD 758

  Fly   524 EDGESGGSGIAKRA 537
            |..|:.|.|..:.|
Mouse   759 EVNETCGEGDGRTA 772

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenB1ANP_524458.1 BAR_ACAPs 18..217 CDD:153287
PH 259..352 CDD:278594 12/76 (16%)
PH_ACAP 260..355 CDD:270070 13/79 (16%)
ArfGap 384..497 CDD:279720 50/112 (45%)
ANK 652..768 CDD:238125
Ank_4 683..736 CDD:290365
ANK repeat 687..713 CDD:293786
ANK repeat 715..746 CDD:293786
Agap1NP_835220.1 Small GTPase-like 66..276
Centaurin_gamma 72..229 CDD:133303
RAS 73..235 CDD:214541
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 267..342
PH_AGAP 344..592 CDD:241281 14/81 (17%)
PH 347..>411 CDD:278594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 407..431
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 497..547 3/21 (14%)
ArfGap 611..725 CDD:279720 53/121 (44%)
Ank_2 736..826 CDD:289560 12/38 (32%)
ANK 736..>825 CDD:238125 12/38 (32%)
ANK repeat 768..799 CDD:293786 1/5 (20%)
ANK 1 768..797 1/5 (20%)
ANK 2 801..830
ANK repeat 801..826 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R258
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

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