Protein Alignment CenB1A and acap3a

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_073795399.1
• Gene: acap3a / 322991
• ZFINID: ZDB-GENE-030131-1711
• Length: 845
• Species: Danio rerio
• Alignment Length: 871
• Identity: 332/871 - (38%)
• Similarity: 486/871 - (55%)
• Gaps: 100/871 - (11%)

  Fly     4 TIEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDLQQ 68
            |::||:|:|||||||..:.:.|:::..:|.:|:|::|||...:::||.||.....|...:.||.|
Zfish     2 TVDFEDCIKDSPRFRANIDEVETEVVEIEAKLDKLVKLCGGMIEAGKAYVTANKLFINGIRDLSQ 66

  Fly    69 HFLDNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKGHFLKVSEG 133
            |...::...:.|.|.....||:..:|.||.|||.|:|.:.|..|||:|:.:.||.|..|.||.|.
Zfish    67 HCKKDQMISDCLEKCGEGLQEIVNYHMILFDQAQRSVKQQLHNFVKEDVRKFKDTKKQFDKVRED 131

  Fly   134 YDNALIKNAQASKNRPQEMQEAANILSASKSCFQHTALDYVNYITLAQARKVPSILSTLLDYYQA 198
            .:.|.:|||||.:|:|.|::||.:.|:.::.||:|.|||||..|.:.||:|...||..:|.:..|
Zfish   132 LEIAQVKNAQAPRNKPHEVEEATSTLNFTRKCFRHLALDYVLQINVLQAKKKFEILDAMLSFMHA 196

  Fly   199 CVTYYHQGFDLCNDFDEFFKNISEDLNALRGDYQQLEKAMQNRHMSVNR--------YCDS---- 251
            ..:.|.||::|.::.|.:.|.::.:|:.|..|....::.|:::|.::.:        |.|.
Zfish   197 QYSLYQQGYNLLDEIDPYMKKLAAELDQLVIDSAMEKREMEHKHATIQQRTLLQDFAYDDPKLEY 261

  Fly   252 NTNSTSNKI-EGYLFKKKSKGFKTWCRRWFYLSDNQLVYRKRSNEDSFSVMEEDLRICSVRPVNE 315
            |.::.:..: ||||||:.|..||||.||||.:.::||||:|:. :||.:|:.||||:|||:|..:
Zfish   262 NVDAPNGLVMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQKKL-KDSLTVVVEDLRLCSVKPCED 325

  Fly   316 GDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQH--DSTHHSRPQSTNAPN-NSLP 377
            .:|||||||:|||||.:|||:|..:...||.|:|.||.:|.:.  |:.:..|...|.:|: :|:.
Zfish   326 IERRFCFEVVSPTKSCMLQAESEKLRQAWIQAVQASIASAYRESPDNYYIERLDRTASPSISSID 390

  Fly   378 A-----KRRIHWEEFLK----IPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKV 433
            :     :|.:..|..|:    :|||..||||...||||||||||:.|||||||:|||||||.|||
Zfish   391 SASESRERSVRGENILQRILSLPGNQQCCDCAQTEPRWASINLGVLLCIECSGIHRSLGVHCSKV 455

  Fly   434 RSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVC 498
            ||||||:||.|.:|:|.||||.::|.|||... ::.|||||........:||||||||||::|:.
Zfish   456 RSLTLDSWEPELLKLMCELGNSIINHIYEGSC-EEQGLKKPAPNSSRQEKEAWIKAKYVEKKFLK 519

  Fly   499 GMPKPQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPK 563
            .|         .|.||       ||..|..              ..|:|..:|.||.....::||
Zfish   520 KM---------MTGEV-------VVNGGRK--------------SERRWNSRKCRRHNSATTVPK 554

  Fly   564 TL--------SDDPSIYNTAKTGDELEDDDD-----DESINI---------PSMSLSISRD---- 602
            |.        |..|:..::|....|.:...:     ||..|:         |.....:|.|
Zfish   555 THRKYRQDPGSASPATLSSATAALERKFRRESLFCPDELDNLFSYFDTGSGPRSPTGLSSDSGLG 619

  Fly   603 -------DLLV---IGDDLALDRLETPGILGSDQESTDGESDAESPEELPFSQLDANQLLYMASV 657
                   |:||   :.|.:..:..|.     |:..|.:.|.:.|:.:.....:|||..|||.|..
Zfish   620 GSTDGSTDVLVFESVVDSVTEEECEV-----SEDSSNEAELEPEASDPEDSRELDAGALLYKACQ 679

  Fly   658 VHNLPVMCMAFALGADKMWKNPQDRQRSFLHQAVISGSVMACEFLLLNGAAIDAVDEMGYSALHI 722
            ..|||||..|.|.|||....|.:|..:|.|.||||.||::||||||.|.|.::..|..|...||.
Zfish   680 ARNLPVMAEALAHGADVNSVNEEDEGKSPLIQAVIGGSLIACEFLLQNSADVNQRDHRGRGPLHH 744

  Fly   723 STAKGHIAQVYLLLKHKAAYDLSSSDGKKALDIAVDQENADIVTLLRLTQLNDEIGPNDEYNGE- 786
            :|..||..||.|.||..|..:....||:..|.|||...||||||||||.::|:|:..::...|:
Zfish   745 ATYLGHTGQVCLFLKRGATQNDGDEDGQDPLSIAVQAANADIVTLLRLARMNEEMRESEGPFGQP 809

  Fly   787 -DETYKNVMKDFSKLPASQTRVLRQR 811
             |.||.::.::||.:.:.....|::|
Zfish   810 GDTTYLDIFREFSHMASHNPEKLKRR 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	74/198 (37%)
		PH_ACAP	260..355	CDD:270070	53/95 (56%)
		ArfGap_ACAP	381..497	CDD:350064	70/119 (59%)
		ANKYR	<647..>768	CDD:440430	59/120 (49%)
		ANK repeat	687..713	CDD:293786	15/25 (60%)
		ANK repeat	715..746	CDD:293786	12/30 (40%)
acap3a	XP_073795399.1	None