Protein Alignment CenB1A and ltc2

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_593790.1
• Gene: ltc2 / 2542216
• PomBaseID: SPAC19A8.02
• Length: 1213
• Species: Schizosaccharomyces pombe
• Alignment Length: 916
• Identity: 182/916 - (19%)
• Similarity: 314/916 - (34%)
• Gaps: 287/916 - (31%)

  Fly     9 ECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDS---GKEYVKNQSAFAMSLWDLQQHF 70
            ||..|||.||..:....:.|:...:.....:..||..::|   .:..|.:.|..||.. ::...|
pombe    21 ECSIDSPSFRASMYYLGNQIKAFNEWSHDFLCCCNKFIESIMAIEPIVASMSLNAMPS-NVASGF 84

  Fly    71 LDNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYK--------GHF 127
            .|...|..|   |:|........:.:.|.||     |||..|:...::..:|.|        ..|
pombe    85 FDPDYATTA---LLHGQDLFRSSYMVQLQQA-----KNLRKFIVAPLDLFRDSKVKPLLQLNDRF 141

  Fly   128 LKVSEGYDNALIKNAQA--SKNRPQEMQEAANILSASKSCFQHTALDYVNYITLAQA-------- 182
            ......||..:::.:..  ||:..|...||.::..|.||.|. .||.||..:|..::
pombe   142 KAEQAKYDAEVLRYSSLGHSKDLSQMRDEAKSLYEARKSYFT-VALQYVVRVTSFRSSIDFIVIE 205

  Fly   183 --------------------RKVPSILSTLLDYYQACVTYYHQGFD-----LCNDFDEFFKNISE 222
                                |.:...|..||.|    .|...:.:.     :.|.||...|.|.:
pombe   206 SICKFSIETFRLTDRLHESNRHINDQLIRLLSY----ETKLKESYPSLKRIVSNVFDRIEKEILK 266

  Fly   223 ------DLNALRGDYQQLEKAMQNRHMSVNRYCDSNTNSTSNKIEGYLFK----KKSKGFKTWCR 277
                  :|:|.|.|.||:              |.:|    :.|.:|:|.:    .|:.....|.:
pombe   267 RVQPPTNLDAYRFDPQQI--------------CQTN----ATKRQGWLLRNISSSKADNKAIWRK 313

  Fly   278 RWFYLSDNQLVYRKRSNEDSFSVMEED---LRIC--SVRPVNEGDRRFCFEVISPTKSHILQADS 337
            .||::.:..:.|  ..|:.:..|.|.:   :.:|  ||.|.|.  |:|||::.:.:.|:||||::
pombe   314 YWFFVDNGYVGY--LINDANGGVFESEKIGVLLCKFSVLPSNH--RKFCFQIKTKSVSYILQAET 374

  Fly   338 ADMLSLWIS----ALQHSIGAAIQHD-------------STHHSRPQSTNAPNNSLP------AK 379
            ...:..|.|    |.:|.|.:.|..:             :|....|| .|..:||..      ..
pombe   375 HMEMLEWGSVINNAREHCINSGISANRILSPTLPSFSAKATSIINPQ-VNGRSNSTGKIGKNYRP 438

  Fly   380 RRIHWEEFLKIPGN-AYCCDCRS------PEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLT 437
            ||.:....|..|.| ......||      |.|::.|.::.              |..:..    .
pombe   439 RRTYSGRLLCGPNNYEVSTIMRSPTISTVPPPKYLSNSIN--------------GAKFLN----P 485

  Fly   438 LDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVCGMPK 502
            |..|...|..::..|.:|.:..:.:                    :||:....           .
pombe   486 LAPWTLVNAPLITNLTHETITSLLD--------------------QEAFFHGN-----------S 519

  Fly   503 PQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKTLSD 567
            |..|||:...   |::.|.|:|                                :|....:.||
pombe   520 PCALLANFWG---SVNYGHVLE--------------------------------RQNVYIEDLS- 548

  Fly   568 DPSIYNTAKTGDELEDDDDDESINIPSMSLSISRDDLLVIGDDLALDRLETPGILGSDQEST--- 629
            :||....|:   |:..:      .:||               :|.|...|..||.|..:.||
pombe   549 NPSYKRLAR---EIHIE------KLPS---------------ELKLRNAEFRGIFGESEASTVLF 589

  Fly   630 --DGESDAESPEELPFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQDRQRSFLHQAVI 692
              ...|..|....:|.......:.:|:...::.| |:...|.:.             |.|:....
pombe   590 VCRVCSKREDQIRMPGRMYCTMKGIYIYYNINGL-VLIEHFPIS-------------SILNVKQF 640

  Fly   693 SGSVMACEFLLLNGAAIDAVDEMGYSALHISTAKGHIAQVYLLLKHKAAYDLSSSDGKKALDIAV 757
            :.:  .|::..:|...|..|    ...|::.::|....::.:||.:..|
pombe   641 AST--KCDYFYMNIQNIGTV----RFRLYLDSSKALTDRLNVLLCNYIA---------------- 683

  Fly   758 DQENADIVTLLRLTQLNDEIGPNDEYNGEDETYKNVMKDFSKLPASQTRVLRQRHDSNTLESQRS 822
            |:.|:.|..|..:.:|||:: ...|..|:|    |.:|.:...|:.:..::|:...|..|    :
pombe   684 DKPNSSIQLLSCIKRLNDDV-KRFERGGDD----NALKSYGVQPSQEDLLIRRGRSSRAL----T 739

  Fly   823 SLTNSD 828
            :|.|.:
pombe   740 NLINKN 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	50/244 (20%)
		PH_ACAP	260..355	CDD:270070	29/107 (27%)
		ArfGap_ACAP	381..497	CDD:350064	17/122 (14%)
		ANKYR	<647..>768	CDD:440430	18/120 (15%)
		ANK repeat	687..713	CDD:293786	4/25 (16%)
		ANK repeat	715..746	CDD:293786	5/30 (17%)
ltc2	NP_593790.1	BAR_SIP3_fungi	31..242	CDD:153293	46/224 (21%)
		PH_SIP3	291..394	CDD:270098	29/106 (27%)
		VASt	779..927	CDD:464975