DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenB1A and Arfgap1

DIOPT Version :9

Sequence 1:	NP_524458.1	Gene:	CenB1A / 42735	FlyBaseID:	FBgn0039056	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	XP_006235793.1	Gene:	Arfgap1 / 246310	RGDID:	708452	Length:	425	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	57/205 - (27%)
Similarity:	84/205 - (40%)	Gaps:	62/205 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 NAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMMELGNEVV 457
            |..|.:|.:..|:|.|:..||.:|:||||.||.||||.|.|||:|:|.|:...::.|...||...
  Rat    19 NNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKF 83

  Fly   458 NRIYEARIGDDCGLKKPTEQCEIGVREAW-IKAKYVERRFVCGMPKPQELLASETAEVLSIDSGG 521
            ....||:  ||             ...:| ::.||                 |..|..|..|
  Rat    84 REFLEAQ--DD-------------YEPSWSLQDKY-----------------SSRAAALFRD--- 113

  Fly   522 VVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKTL-------SDDPSIYNTAKTGD 579
                         |.|||:.|  ::|:::....:......||||       :..|.  |...:||
  Rat   114 -------------KVATLAEG--KEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQ--NVTTSGD 161

  Fly   580 ELEDD--DDD 587
            :..:|  :||
  Rat   162 KAFEDWLNDD 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287
		PH	259..352	CDD:278594
		PH_ACAP	260..355	CDD:270070
		ArfGap	384..497	CDD:279720	36/104 (35%)
		ANK	652..768	CDD:238125
		Ank_4	683..736	CDD:290365
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
Arfgap1	XP_006235793.1	ArfGap	7..114	CDD:279720	40/142 (28%)
Arfgap1	XP_006235793.1	DUF4048	<325..376	CDD:289997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900