DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenB1A and W09D10.1

DIOPT Version :9

Sequence 1:	NP_524458.1	Gene:	CenB1A / 42735	FlyBaseID:	FBgn0039056	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_499364.1	Gene:	W09D10.1 / 176499	WormBaseID:	WBGene00012359	Length:	495	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	85/303 - (28%)
Similarity:	124/303 - (40%)	Gaps:	84/303 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 EFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMM 450
            :.||...|.||.||::..||||:.|||:.:||.|:|:||:||||.|||||:.||:|..|.|:.|.
Worm    22 DMLKEEENKYCADCQAKTPRWAAWNLGVFICIRCAGIHRNLGVHISKVRSVNLDSWTPEQVQTMR 86

  Fly   451 ELGNEVVNRIYEARIGDDCGLKKPT--EQCEIGVREAWIKAKYVERRFVCGMPK------PQELL 507
            .:|||...::||..:  ....::||  :|.|..:|..:.:.:|:.|.||  .|:      |:.|.
Worm    87 VMGNEKARQVYEHDL--PAQFRRPTNDQQMEQFIRSKYEQKRYILRDFV--YPRVDASQLPKSLS 147

  Fly   508 ASET---AEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKTL--SD 567
            .::.   ..|::|.|.|   ...|.|...|..|.                     :.|..|  ||
Worm   148 QAQKKVGTPVVNIASRG---SSSSNGHSTASAAA---------------------AAPSLLDFSD 188

  Fly   568 DPSIYNTAKTGDELEDDDDDESIN--IPSMSLSISRDDLLVIG---------------------- 608
            .|:....||....|.||.|..|:.  .|:.:.:...||....|
Worm   189 PPASTTPAKKAVNLFDDFDGLSLGPAAPAAAPAALNDDFDDFGSFVSANSQNAQQNAQSLGGGFA 253

  Fly   609 -------------------DDLALDRLETPGILGSDQESTDGE 632
                               |||.......|...||||:.|:.:
Worm   254 DFSSAPTTAAAAPSASSGLDDLTALSSTAPATNGSDQKKTNAD 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287
		PH	259..352	CDD:278594
		PH_ACAP	260..355	CDD:270070
		ArfGap	384..497	CDD:279720	47/112 (42%)
		ANK	652..768	CDD:238125
		Ank_4	683..736	CDD:290365
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
W09D10.1	NP_499364.1	ArfGap_SMAP	20..122	CDD:350068	45/101 (45%)
W09D10.1	NP_499364.1	DEC-1_N	<301..>415	CDD:368028
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D751525at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820