DRSC/TRiP Functional Genomics Resources

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Protein Alignment CenB1A and Arap3

DIOPT Version :9

Sequence 1:NP_524458.1 Gene:CenB1A / 42735 FlyBaseID:FBgn0039056 Length:828 Species:Drosophila melanogaster
Sequence 2:XP_006525549.1 Gene:Arap3 / 106952 MGIID:2147274 Length:1539 Species:Mus musculus


Alignment Length:446 Identity:103/446 - (23%)
Similarity:169/446 - (37%) Gaps:152/446 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   294 NEDSFS----VMEEDLRICSVRPVNEGDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGA 354
            :|.:||    :...:|:.||||......    |::::|.:.....|:|......|.:|||.::..
Mouse   420 SEQAFSLGIGICFIELQGCSVRETKSRS----FDLLTPHRCFSFTAESGGARQSWAAALQEAVTE 480

  Fly   355 AIQHDSTHHSRPQSTNAPNNSLPAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCIEC 419
            .:                 :......:: |..    |.|.:|.|||:..|.||::|||:.:|.:|
Mouse   481 TL-----------------SDYEVAEKV-WSN----PANRHCADCRASRPDWAAVNLGVVICKQC 523

  Fly   420 SGVHRSLGVHYSKVRSLTLD--AWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGV 482
            :|.||:||...|||:||.||  .|.:|.|::.:.|||:..|..:...:....||...:..   |.
Mouse   524 AGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANCFWAGALPPGEGLHPDSAP---GP 585

  Fly   483 REAWIKAKYVERRFVCGM---PKP---------QELLAS--------ETAEVLSIDSGGVVEDGE 527
            |     .:::.|::..|:   |.|         |.|.|:        ..|::|.:::    .:||
Mouse   586 R-----GEFISRKYKLGLFRKPHPRHPDHSQLLQALCAAMAGPNLLKNMAQLLCVET----SEGE 641

  Fly   528 SGGSGIAKRAT-LSLGGTRKWAVKKLRRRQKQRSIPKTLSDDPSIYNTAKTGDELEDDDDDESIN 591
            ...|..|...: |||                   :|   ||.|.:||               .:.
Mouse   642 EPLSPSALNGSLLSL-------------------LP---SDSPGVYN---------------EVV 669

  Fly   592 IP----------SMS-------LSISRDDLLVIGDDLALDRLETPGILGSDQESTDGESDAESPE 639
            :|          |:|       |...||         |..||..  :||:..|....||   |||
Mouse   670 VPATYRGFLYCGSISNKAGAPPLRRGRD---------APPRLWC--VLGAALEMFASES---SPE 720

  Fly   640 ELPFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQDRQR-SFLHQAVISG 694
            .|              |::....::|    ||......:|.|..| .|..:.:::|
Mouse   721 PL--------------SLLQPQDIVC----LGVSPPPADPGDLDRFPFSFELILTG 758

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CenB1ANP_524458.1 BAR_ACAPs 18..217 CDD:153287
PH 259..352 CDD:278594 16/61 (26%)
PH_ACAP 260..355 CDD:270070 16/64 (25%)
ArfGap 384..497 CDD:279720 39/114 (34%)
ANK 652..768 CDD:238125 9/44 (20%)
Ank_4 683..736 CDD:290365 3/13 (23%)
ANK repeat 687..713 CDD:293786 1/8 (13%)
ANK repeat 715..746 CDD:293786
Arap3XP_006525549.1 SAM_Arap1,2,3 4..66 CDD:188889
PHA03247 <81..312 CDD:223021
PH1_ARAP 285..377 CDD:270073
PH2_ARAP 392..475 CDD:270074 14/58 (24%)
ArfGap_ARAP3 485..600 CDD:350089 40/127 (31%)
PH-like 671..783 CDD:388408 27/120 (23%)
PH-like 798..891 CDD:388408
RhoGAP_ARAP 906..1081 CDD:239850
Ubiquitin_like_fold 1113..1210 CDD:391949
PH5_ARAP 1210..1326 CDD:270079
PLN02983 <1472..>1538 CDD:215533
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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