DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CenB1A and smap2

DIOPT Version :9

Sequence 1:	NP_524458.1	Gene:	CenB1A / 42735	FlyBaseID:	FBgn0039056	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	XP_002938524.3	Gene:	smap2 / 100496482	XenbaseID:	XB-GENE-5817085	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	309	Identity:	86/309 - (27%)
Similarity:	135/309 - (43%)	Gaps:	62/309 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 EFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENVKVMM 450
            |.|....|.:|.||.:..|||||.|:|:.:||.|:||||:||||.|:|:|:.||.|..|.::.|.
Frog    18 ELLLREENKFCADCLAKGPRWASWNIGVFVCIRCAGVHRNLGVHISRVKSVNLDQWTQEQIQCME 82

  Fly   451 ELGNEVVNRIYEARIGDDCGLKKPTEQC-EIGVREAWIKAKYVERRF-VCGMPKPQELLASETAE 513
            |:||....|:|||.:.|:. ::..|:|. |:.:||.:.|.||::|.. :....|.::....::..
Frog    83 EMGNGKAKRLYEAFLPDNF-IRPQTDQAVEVFIREKYEKKKYMDRSVDLSAFRKEKDTKWKKSES 146

  Fly   514 VLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPKT-------LSDDPSI 571
            ...|.||.|:.:                  ..|...||...:|.:.|.|||       |..|..:
Frog   147 APEIKSGPVIFE------------------KVKLPQKKDETQQLKVSPPKTVEPVMDLLGLDVPV 193

  Fly   572 YNTAKTGDELEDDDDDESINIPSMSLSISRDDLLVIGD--DLALDRLETPGILGSDQE------- 627
            .|:...|.             ||.||   ..:|.:.|.  .:::.:...||:.||...
Frog   194 ANSVPNGK-------------PSTSL---EKELDLFGSVAPISISKSSQPGLPGSSGSVPENLNL 242

  Fly   628 --STDGESDAESPEELPFSQL------DANQLLYMASVVHNLPVMCMAF 668
              ...|:|:....::|....:      .|.|:...|..|...|.. ||:
Frog   243 FPEPSGKSEDGGKKQLSKDSILSLYGSQAPQIPAQAGAVFMAPAQ-MAY 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287
		PH	259..352	CDD:278594
		PH_ACAP	260..355	CDD:270070
		ArfGap	384..497	CDD:279720	49/112 (44%)
		ANK	652..768	CDD:238125	5/17 (29%)
		Ank_4	683..736	CDD:290365
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
smap2	XP_002938524.3	ArfGap_SMAP2	16..122	CDD:350083	46/104 (44%)
smap2	XP_002938524.3	Med15	270..>411	CDD:312941	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910