Protein Alignment CenB1A and acap3

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_012821390.1
• Gene: acap3 / 100127680
• XenbaseID: XB-GENE-1013301
• Length: 871
• Species: Xenopus tropicalis
• Alignment Length: 912
• Identity: 338/912 - (37%)
• Similarity: 495/912 - (54%)
• Gaps: 143/912 - (15%)

  Fly     4 TIEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDLQQ 68
            |::||||:|||||||..:.:.|:|:..:|.:|:|::|||:..:::||.|:.....|...:.||.|
 Frog     2 TVDFEECIKDSPRFRAAIDEVETDVVEIEAKLDKLVKLCSSMLEAGKTYLTTNKHFVSGIRDLSQ 66

  Fly    69 HFLDNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKGHFLKVSEG 133
            ....::.....|.|.....|||..:|.||.|||.|:|.:.|.:|||||:.:.|:.|..|.||.|.
 Frog    67 QCKKDEMISECLDKFGDSLQEMVNYHMILFDQAQRSVRQQLHMFVKDDVRKFKESKKQFDKVRED 131

  Fly   134 YDNALIKNAQASKNRPQEMQEAANILSASKSCFQHTALDYVNYITLAQARKVPSILSTLLDYYQA 198
            .|.||:|||||.:::|.|::||::.|:.::.||:|.|||||..|.:.||:|...||..:|.:..|
 Frog   132 LDIALVKNAQAPRHKPHEVEEASSTLTITRKCFRHLALDYVLQINVLQAKKKFEILDAMLSFMHA 196

  Fly   199 CVTYYHQGFDLCNDFDEFFKNISEDLNALRGDYQQLEKAMQNRHMSVNR--------YCDS---- 251
            ..|::.||:.|.|:.:.:.|.::.:|:.|..|....::.|:::|.::.:        |.||
 Frog   197 QYTFFQQGYSLLNELNPYMKQLASELDQLVIDSAVEKREMEHKHATIQQRTLLQDFSYDDSKADF 261

  Fly   252 NTNSTSNKI-EGYLFKKKSKGFKTWCRRWFYLSDNQLVYRKRSNEDSFSVMEEDLRICSVRPVNE 315
            |.::.:..: ||||||:.|..||||.||||.:.::||||:|:. :|..:|:.||||:|:|:|..:
 Frog   262 NVDAPNGVVMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQKKL-KDVLTVVVEDLRLCTVKPCED 325

  Fly   316 GDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQH--DSTHHSRPQSTNAPNNSL-- 376
            .:|||||||:||:||.:|||||..:...||.|:|.||.:|.:.  |:.:..|...|.:|:.|.
 Frog   326 IERRFCFEVVSPSKSCMLQADSEKLRQSWIQAVQASIASAYRETPDNYYIERLDRTASPSTSSID 390

  Fly   377 ----PAKRRIHWEEFLK----IPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKV 433
                ..:|.:..|..|:    |.||..||||...:||||||||||||||||||:|||||||:|||
 Frog   391 SASDSRERSVKGESILQRVQSIAGNDQCCDCGQTDPRWASINLGITLCIECSGIHRSLGVHFSKV 455

  Fly   434 RSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFVC 498
            ||||||:||.|.:|:|.||||..:|:||||:. :..||||||..|....:|.||||||||::|:
 Frog   456 RSLTLDSWEPELLKLMCELGNSTINQIYEAKC-EHLGLKKPTSGCSRQDKEIWIKAKYVEKKFL- 518

  Fly   499 GMPKPQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRSIPK 563
                 :.|.|.|            ||:...               .::|:|||..|......:|.
 Frog   519 -----KRLGAVE------------VENDRK---------------PQRWSVKKCHRNNSTTKVPS 551

  Fly   564 TL--------SDDPSIYNTAKT------------GDELED-------DDDDESIN---------- 591
            |.        |..|::.::|.|            .|||:.       .....|:|
 Frog   552 TRRKYRHEMGSASPAMLSSAATLERKFRRDSLFCPDELDSLFSYFDTGSGPRSVNPLPAQHPLPA 616

  Fly   592 -----------------IPSMSLSI---------SRDDLLVIG---DDLALDRLETPGILGSDQE 627
                             :|...||.         ..:|:||.|   |.:..:..|.       .|
 Frog   617 VPWTGSGAEPGGSAMPFLPDGGLSSDSGLGGSTDGSNDILVFGAVVDSVTEEECEV-------SE 674

  Fly   628 STDGESDAE----SPEELPFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQDRQRSFLH 688
            .:.||.:.|    .||:|  .:|....|::.||...|||||..|.|.||:..|.|.:|..::.|.
 Frog   675 DSSGEVETEQEPSDPEDL--RELHPGLLMFRASRTRNLPVMAEALANGANVNWVNDEDESKTPLI 737

  Fly   689 QAVISGSVMACEFLLLNGAAIDAVDEMGYSALHISTAKGHIAQVYLLLKHKAAYDLSSSDGKKAL 753
            ||||.||::||||||.|||.::..|..|.:.:|.:|..||..||.|.||..|.......||:..|
 Frog   738 QAVIGGSLIACEFLLQNGADVNQTDMRGRAPIHHATYLGHTGQVCLFLKRGANQHAVDEDGQDPL 802

  Fly   754 DIAVDQENADIVTLLRLTQLNDEIGPNDEYNGE--DETYKNVMKDFSKLPASQTRVLRQR--HDS 814
            .|||...||||||||||.::|:|:...:...|:  |.||.::.::||.:.::....|.:|  |.|
 Frog   803 SIAVQAANADIVTLLRLARMNEEMREAEGPFGQPGDTTYLDIFREFSHMASNNPEKLSRRSVHFS 867

  Fly   815 NT 816
            |:
 Frog   868 NS 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	75/198 (38%)
		PH_ACAP	260..355	CDD:270070	51/95 (54%)
		ArfGap_ACAP	381..497	CDD:350064	73/119 (61%)
		ANKYR	<647..>768	CDD:440430	55/120 (46%)
		ANK repeat	687..713	CDD:293786	16/25 (64%)
		ANK repeat	715..746	CDD:293786	11/30 (37%)
acap3	XP_012821390.1	BAR_ACAP3	16..215	CDD:153321	75/198 (38%)
		PH_ACAP	271..367	CDD:270070	52/96 (54%)
		ArfGap_ACAP3	403..518	CDD:350075	73/115 (63%)
		ANKYR	<680..>817	CDD:440430	60/138 (43%)
		ANK repeat	729..762	CDD:293786	17/32 (53%)
		ANK repeat	764..795	CDD:293786	11/30 (37%)