Protein Alignment CenB1A and appl1

DIOPT Version :9

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_031757118.1
• Gene: appl1 / 100038055
• XenbaseID: XB-GENE-855791
• Length: 708
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 118/562 - (20%)
• Similarity: 230/562 - (40%)
• Gaps: 101/562 - (17%)

  Fly     5 IEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSL------ 63
            :..||.|:|||:.|..:...|.|...:.....::........|:     :|:.:.|..|
 Frog     7 LPIEETLEDSPQTRSLLGVFEEDAAAISSYSNQLFHAMRRIYDA-----QNELSAATHLTSKLLK 66

  Fly    64 -WDLQQHFL--DNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKG 125
             ::.|:..|  |::...:.|.:......|::..|.:|..|.:..::..:..|.:.|:.::...|.
 Frog    67 EYEKQRFPLGGDDEVMTSTLQQFSKVIDELSSCHAVLSTQLADAMMFPIGQFKERDLKEILTLKE 131

  Fly   126 HFLKVSEGYDNALIKNAQASKNRPQE---MQEAANILSASKSCFQH-TALDYVNYITLAQARKVP 186
            .|...|..:|.|:.:.::.||.|..|   .:...::.:|.|.  || |.:.|...:...|.:|..
 Frog   132 VFQIASNDHDVAINRYSRLSKRRENEKTKFEATEDVYTARKK--QHQTMMHYFCALNTIQYKKKT 194

  Fly   187 SILSTLLDYYQACVTYYHQGFD-LCNDFDEFFKNISEDLNALRGDYQQLEKAMQNRHMSVN---- 246
            :||..||.|.||.:.::..|.: |.:..:||..||...:.::|   :::::.|:|...::.
 Frog   195 AILEPLLGYMQAQINFFKMGSENLNSQLEEFLTNIGTSVQSVR---REMDQDMENMQQTIQDMEA 256

  Fly   247 ------------RYCDSNTNSTSNKIEGYLFKKKSKGF--KTWCRRWFYLSDNQLVYRKRSNEDS 297
                        :....|.|.|  :..|||..:...|.  .:|.|.:::.....|:.:.|.:...
 Frog   257 ASEPLYLPDPDLKKLPVNRNLT--RKAGYLNIRNKTGLVSSSWDRHYYFTQGGNLMSQARGDVAG 319

  Fly   298 FSVMEEDLRICSVRPVNEGDRRFCFEV--ISPTKSHILQADSADMLSLWISALQHSIGAAIQHDS 360
            ..||  |:..|||..::..|||:||::  ....||.||||:|......|||.: ::|...|...
 Frog   320 GLVM--DIDNCSVMAIDSEDRRYCFQITAFDGKKSVILQAESKKDCEEWISTI-NNISKRIYLT- 380

  Fly   361 THHSRPQSTNAPNNS--------LPAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCI 417
               ..|:.|.|..|.        .|:.::.|......:|...:.....|
 Frog   381 ---ENPEETAARVNQSALEAVTPSPSFQQRHESMRPAVPSRPHATRTSS---------------- 426

  Fly   418 ECSGVHRSLGVHYSKVRSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGV 482
              :|   |:|...|.:.:|:||:..:.:..:..    ::::.:.|.:.|      :|....:.|.
 Frog   427 --TG---SIGSDSSALTALSLDSIVAPDTPIQF----DIISPVSEDQSG------QPRTPGQTGR 476

  Fly   483 R-----EAWIKAK----YVERRFVCGMPKPQELLASETAEVL 515
            |     |:..|::    .:.:.|:.......|:.:.|:|||:
 Frog   477 RTNPFGESGEKSESEDSILHQLFIVRFLGSMEVKSDESAEVV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	44/212 (21%)
		PH	259..352	CDD:278594	29/96 (30%)
		PH_ACAP	260..355	CDD:270070	30/98 (31%)
		ArfGap	384..497	CDD:279720	16/121 (13%)
		ANK	652..768	CDD:238125
		Ank_4	683..736	CDD:290365
		ANK repeat	687..713	CDD:293786
		ANK repeat	715..746	CDD:293786
appl1	XP_031757118.1	BAR_APPL1	20..234	CDD:153315	47/220 (21%)
		BAR-PH_APPL	252..376	CDD:270067	33/128 (26%)
		PTB_APPL	487..622	CDD:269980	7/32 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000