Protein Alignment CenB1A and acap3b

DIOPT Version :10

• Sequence 1: NP_524458.1
• Gene: CenB1A / 42735
• FlyBaseID: FBgn0039056
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001076484.2
• Gene: acap3b / 100009646
• ZFINID: ZDB-GENE-070209-274
• Length: 843
• Species: Danio rerio
• Alignment Length: 881
• Identity: 335/881 - (38%)
• Similarity: 484/881 - (54%)
• Gaps: 112/881 - (12%)

  Fly     4 TIEFEECLKDSPRFRQFVSKEESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWDLQQ 68
            |::||||:|||||||..:.:.|:|:..:|.:|:|::|||:..:::|:.|......|...:.||..
Zfish     2 TVDFEECIKDSPRFRANIDEVETDVVEIEAKLDKLVKLCSGMIEAGRAYATANKLFVNGIRDLSH 66

  Fly    69 HFLDNKNAHNALGKLIHCFQEMNKFHTILLDQASRTVLKNLSVFVKDDINQVKDYKGHFLKVSEG 133
            |....:.....|.|.....||:..:|.||.|||.|:|.:.|..|||:|:.:.|:.|..|.||.|.
Zfish    67 HCKKEEMISECLEKCGESLQEIVNYHMILFDQAQRSVKQQLHSFVKEDVRKFKETKKQFDKVRED 131

  Fly   134 YDNALIKNAQASKNRPQEMQEAANILSASKSCFQHTALDYVNYITLAQARKVPSILSTLLDYYQA 198
            .:.|.:|||||.:|:|.|::||.:.|..::.||:|.|||||..|.:.||:|...||.::|.:.||
Zfish   132 MEIAQVKNAQAPRNKPHEVEEATSTLITTRKCFRHLALDYVLQINVLQAKKKFEILDSMLSFMQA 196

  Fly   199 CVTYYHQGFDLCNDFDEFFKNISEDLNALRGDYQQLEKAMQNRHMSVNR--------YCDS---- 251
            ....:||||:|.::.|.:.|.::.:|:.|..|....::.|:::|.::.:        |.||
Zfish   197 QYGLFHQGFNLLDEIDPYMKKLAAELDQLVIDSAMEKREMEHKHATIQQRTLMQDFAYDDSKVEF 261

  Fly   252 NTNSTSNKI-EGYLFKKKSKGFKTWCRRWFYLSDNQLVYRKRSNEDSFSVMEEDLRICSVRPVNE 315
            |.::.:..: ||||||:.|..||||.||||.:.::||||:||. :|:.:|:.||||:|||:|..:
Zfish   262 NVDAPNGVVMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQKRL-KDALTVVVEDLRLCSVKPCED 325

  Fly   316 GDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQHDSTHH--------SRPQSTNAP 372
            .:|||||||:|||||.:|||:|..:...||.|:|.||.:|.:..|.::        :.|.:::..
Zfish   326 IERRFCFEVVSPTKSCMLQAESEKLRQAWIQAVQASIASAYREISENYYIERLDRTASPSTSSID 390

  Fly   373 NNSLPAKRRIHWEEFLK----IPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKV 433
            :.|.|.:|.:..:..|:    :|||..||||...:||||||||||.|||||||:|||||||.|||
Zfish   391 SASEPRERVVRGDSILQRVQCLPGNEICCDCGQSDPRWASINLGILLCIECSGIHRSLGVHCSKV 455

  Fly   434 RSLTLDAWESENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRF-- 496
            ||||||.||.|.:|:|.||||.|:|:|||... ::.|||||........:|||||||||||:|
Zfish   456 RSLTLDTWEPELMKLMCELGNTVINQIYEGAC-EEQGLKKPGPNSSRQEKEAWIKAKYVERKFLK 519

  Fly   497 -VCGMPKPQELLASETAEVLSIDSGGVVEDGESGGSGIAKRATLSLGGTRKWAVKKLRRRQKQRS 560
             :||                   |..::|.|..               :..|:|||.||......
Zfish   520 KMCG-------------------SEALLEGGRK---------------SHHWSVKKCRRHNSSIR 550

  Fly   561 IPKT---LSDDPSIYNTAKTG----------DELEDDDDDESI----NIPSMSLSISRD------ 602
            .|||   ...|.:|.:.....          :.|...|:.:|:    :..|...|:|.|
Zfish   551 APKTRRKYRHDAAIMSPGNLSAAAAAAKFRRESLFCPDELDSLFSYFDTGSGPRSLSSDSGLGGS 615

  Fly   603 -----DLLVIGDDLALDRLETPGILGSDQES--TDGESDAESPEELPFSQLDANQLLYMASVVHN 660
                 |:||.|.  .:|.:.......||:.|  .|.|.:|..||:  ..:||.|.||:.||...|
Zfish   616 TDGSTDILVFGS--VVDSVTEEECEDSDESSGEVDIEQEASDPED--GRELDPNTLLHKASRARN 676

  Fly   661 LPVMCMAFALGADKMWKNPQDRQRSFLHQAVISGSVMACEFLLLNGAAIDAVDEMGYSALHISTA 725
            :|||..|.|.|||....:.:|..:|.|.|||..||::||||||.|||.::..|..|...||.:|.
Zfish   677 MPVMAEALAHGADVNSVSEEDESKSPLIQAVTGGSLIACEFLLQNGADVNQRDIRGRGPLHHATC 741

  Fly   726 KGHIAQVYLLLKHKAAYDLSSSDGKKALDIAVDQENADIVTLLRLTQLNDEIGPNDEYNGEDETY 790
            .||..||.|.||..|.......||:..|.|||...||||||||||.::|:|:...|...|:.:
Zfish   742 LGHTGQVCLFLKRGAGQMEVDEDGQDPLSIAVQAANADIVTLLRLARMNEEMREADGPLGQPD-- 804

  Fly   791 KNVMKDFSKLPASQTRVLRQRHDSNTLESQRSSLTN 826
                   :.:|.|..||.|:     :|.:...||::
Zfish   805 -------ASVPVSPLRVKRK-----SLRASPRSLSS 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CenB1A	NP_524458.1	BAR_ACAPs	18..217	CDD:153287	73/198 (37%)
		PH_ACAP	260..355	CDD:270070	53/95 (56%)
		ArfGap_ACAP	381..497	CDD:350064	72/122 (59%)
		ANKYR	<647..>768	CDD:440430	57/120 (48%)
		ANK repeat	687..713	CDD:293786	15/25 (60%)
		ANK repeat	715..746	CDD:293786	12/30 (40%)
acap3b	NP_001076484.2	None