Protein Alignment Rassf and RASSF2

DIOPT Version :10

• Sequence 1: NP_651126.3
• Gene: Rassf / 42734
• FlyBaseID: FBgn0039055
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_011527712.1
• Gene: RASSF2 / 9770
• HGNCID: 9883
• Length: 328
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 87/274 - (31%)
• Similarity: 148/274 - (54%)
• Gaps: 36/274 - (13%)

  Fly   550 QRYIQIQMDCYPKENVAAASEGESSRADAPSITSGAAAGDEL--------------TQTEDLYTA 600
            :|.|::||            :.::.|...|..:|...:|..|              .|..::...
Human    63 RRPIRLQM------------QDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAP 115

  Fly   601 SEGVDGPDGDG--SAGLH-VTEDGVVLRRPPRTGASAIKRRSGNRRSRTKLKR----RCSINGHY 658
            .||...|...|  |.||. :.||...|.   ||.:....||.||.|:.:..:|    |.|||||:
Human   116 PEGDQMPSSTGTYSRGLKPLQEDTPQLM---RTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHF 177

  Fly   659 YNRETSFFTPPYGSQMSVWVSSMVTTTEVINLVLEKYKVDSSPGNFSLFIVRDNGEQKRLKDDEY 723
            ||.:||.|||.|||..:|.::|.:||.:|:.|:|.|:|:::|...|:|::|..:||:::||..:|
Human   178 YNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY 242

  Fly   724 PLITRVTLGPHEDVARIFLVDSRKTDEISNEVAQFLNLSLPECRAILERYDQELAREVAKIKERY 788
            |||.|:..||.|.::::||::..:.:|::.:|||::...:|..::.:::..:|..|||.|:..:|
Human   243 PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKY 307

  Fly   789 AELRRRIVSRMESL 802
            ..||..|..|:|.:
Human   308 TVLRLMIRQRLEEI 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785
		RA_RASSF2_like	660..746	CDD:340482	36/85 (42%)
		SARAH_RASSF2-like	757..801	CDD:439180	12/43 (28%)
RASSF2	XP_011527712.1	RA_RASSF2	179..265	CDD:340741	36/85 (42%)
		SARAH_RASSF2	276..321	CDD:439187	13/44 (30%)