DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rassf and Rassf5

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_062238.1	Gene:	Rassf5 / 54355	RGDID:	621694	Length:	413	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	89/393 - (22%)
Similarity:	153/393 - (38%)	Gaps:	108/393 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 NCEHALRSIDPTLINDTMNLRSSVGSPHSAQRQYALQKSGSATVTSRDQKKPYQQ---GRQLFEK 510
            :|.|| |.:.|.|   ...||...||..                 .||.:..::|   .|.|.|:
  Rat    71 DCRHA-RPVRPGL---QQRLRRRPGSHR-----------------PRDVRSIFEQPQDPRVLAER 114

  Fly   511 GINRS------KSGPS----CFVYSDSDDDDEATLRPQRMATIRRSDIPQRYIQIQMDCYPKENV 565
            |....      :.||.    |        ..|...:..|.|..:.:..|:....||:||..||..
  Rat   115 GEGHRFAELALRGGPGWCDLC--------GREVLRQALRCANCKFTCHPECRSLIQLDCRQKEGP 171

  Fly   566 AAASEGESSRADAPSITSGAAAG----------DELTQTEDLYTASEGVDGPDGDGSAGLHVTED 620
            |...:...|.. .|:........          .|:.|..|.|.:.|       ....|:.::||
  Rat   172 ALDRQSPESTL-TPTFNKNVCKAVEETQHPPTIQEIKQKIDSYNSRE-------KHCLGMKLSED 228

  Fly   621 G---------VVLRRP--------PRTGASAIKRRSGNRRSRTKLKRRCSINGHYYNRETSFFTP 668
            |         :.||||        |::...|||  ..|..:.|             ::.|||:.
  Rat   229 GTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIK--EVNPAATT-------------DKRTSFYL- 277

  Fly   669 PYGSQMSVWVSSMVTTTEVINLVLEKYKVDSSPGNFSLF-IVRDNGEQ--KRLKDDEYPLITRVT 730
            |..:...:.:||..|.:|||..:|:|:.|..:|..|:|| .:..:|:.  ::|...:.||..|:.
  Rat   278 PLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLL 342

  Fly   731 LGPHEDVARIFLVDSRKTDEISNEVAQFLNLSLPECR---AILERYDQELAREVAKIKERYAELR 792
            .||..||.. |::...:|.::..:.     .|:||.:   .|||:.:|:   ::.:::::|.:.|
  Rat   343 AGPDTDVLS-FVLKENETGDVEWDA-----FSIPELQNFLTILEKEEQD---KIHQLQKKYNKFR 398

  Fly   793 RRI 795
            :::
  Rat   399 QKL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785
		UBQ	660..744	CDD:294102	27/86 (31%)
		Nore1-SARAH	762..799	CDD:293125	9/37 (24%)
Rassf5	NP_062238.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..105		12/54 (22%)
		C1	118..166	CDD:294036	10/55 (18%)
		RASSF1_RA	267..360	CDD:176373	28/107 (26%)
		Nore1-SARAH	366..405	CDD:293125	9/44 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351805
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740