DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rassf and CRIP3

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_996805.2	Gene:	CRIP3 / 401262	HGNCID:	17751	Length:	204	Species:	Homo sapiens

Alignment Length:	106	Identity:	47/106 - (44%)
Similarity:	58/106 - (54%)	Gaps:	10/106 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WKCHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHAEHKSVPYCHVPCYGALFGPQLF 66
            |.|.:|.:||:|||:..|:|.:||..||:||.|...|:||.||||...||||.|||||||||:
Human     3 WTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPR-- 65

  Fly    67 GHGTRVESHKSY------GVKGAQKPTGAQANGPPLPRDHL 101
              |..:....||      ...|...|....:..||.||..|
Human    66 --GVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGL 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785	28/52 (54%)
		UBQ	660..744	CDD:294102
		Nore1-SARAH	762..799	CDD:293125
CRIP3	NP_996805.2	LIM1_TLP	5..58	CDD:188860	28/52 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..112		7/21 (33%)
		LIM2_TLP	124..177	CDD:188861
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7828
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.810