DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rassf and Rassf3

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_001102217.2	Gene:	Rassf3 / 362886	RGDID:	1311450	Length:	233	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	56/234 - (23%)
Similarity:	91/234 - (38%)	Gaps:	52/234 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   601 SEGVDGPDGDGSAGLHVTEDGVVLRRPP---RTGASAIKRRSG-----------------NRRSR 645
            |.|....:.|..............|.||   |:|...:::...                 |....
  Rat     2 SSGYSSLEEDAEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNLAVT 66

  Fly   646 TKLKRRCSINGHYYNRETSFF-----------TP----PYGSQMSVWVSSMVTTTEVINLVLEKY 695
            .|||...:.||.|    |.|.           ||    ..|...::.:||..|..:||:.:|:|:
  Rat    67 DKLKMTLNSNGIY----TGFIKVQMELCKPAQTPANPSSSGCMNTLHISSTNTVGDVIDALLKKF 127

  Fly   696 KVDSSPGNFSLFIVRDNGEQK----RLKDDEYPLITRVTLGPHEDVARIFLVDSRKTDEISNEVA 756
            :|..||..|:|: .|.:.|.:    :|.|.|:||..|:..||..|.....|.:        :|:.
  Rat   128 QVTESPTKFALY-KRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLRE--------HEIG 183

  Fly   757 QFLNLSLPECRAILERYDQELAREVAKIKERYAELRRRI 795
            ::...||||.:..|...|:|...::..:|.||...|:::
  Rat   184 EWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785
		UBQ	660..744	CDD:294102	29/102 (28%)
		Nore1-SARAH	762..799	CDD:293125	11/34 (32%)
Rassf3	NP_001102217.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351801
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740