DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rassf and Rassf6

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	XP_008768258.1	Gene:	Rassf6 / 305251	RGDID:	1566082	Length:	404	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	86/280 - (30%)
Similarity:	138/280 - (49%)	Gaps:	56/280 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 VYSDSDDDDEATLRPQRMATIRRSDIPQRYIQIQMDCYPKENVAAASEGESSRADAPSITSGAAA 587
            :|..|:.|....|.|:...|      |:.|    :.||                   |:....|
  Rat   170 LYRISEMDKTQALAPEARHT------PEDY----LSCY-------------------SVLKQCA- 204

  Fly   588 GDELTQTEDLY-TASEGVDGPDGDGSAGLHVTEDGVVLRRPPRTGASAIKRRSGNRRSRTKLKRR 651
             ||..::..|| |.||                  ..::|:..|......|.|.|     |..|.|
  Rat   205 -DEEPESPLLYRTVSE------------------AALVRKRMRAPEMYRKDRMG-----TLAKHR 245

  Fly   652 CSINGHYYNRETSFFTPPYGSQMSVWVSSMVTTTEVINLVLEKYKVDSSPGNFSLFIVRDNGEQK 716
            .|||||.|:.|||.|||.:||:..|..:|::.|.|||..:|:|:|:::||.:|:|:|:...||::
  Rat   246 ASINGHVYDHETSIFTPTFGSETKVRANSIMKTEEVIKQLLQKFKIENSPRDFALYIIFGTGEKR 310

  Fly   717 RLKDDEYPLITRVTLGPHEDVARIFLVDSRKTDEISNEVAQFLNLSLPECRAILERYDQELAREV 781
            :||..:.||:.|:..||.:..|||||:| :..:|||::||.::|......::||:|.|:|...|:
  Rat   311 KLKKTDVPLLQRLIQGPSKSNARIFLMD-KDAEEISSDVAPYINFHFSFLKSILQRLDEEEKMEI 374

  Fly   782 AKIKERYAELRRRIVSRMES 801
            .:|..::...|..|:..::|
  Rat   375 ERIMAKFNTERAFILKCLQS 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785
		UBQ	660..744	CDD:294102	36/83 (43%)
		Nore1-SARAH	762..799	CDD:293125	9/36 (25%)
Rassf6	XP_008768258.1	UBQ	254..340	CDD:294102	37/86 (43%)
Rassf6	XP_008768258.1	Nore1-SARAH	354..392	CDD:293125	9/37 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351804
Domainoid	1	1.000	77	1.000	Domainoid score	I8636
eggNOG	1	0.900	-	-		E1_KOG4239
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4019
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1043350at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46000
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22738
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.860