DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rassf and CSRP1

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_001180500.1	Gene:	CSRP1 / 1465	HGNCID:	2469	Length:	193	Species:	Homo sapiens

Alignment Length:	97	Identity:	33/97 - (34%)
Similarity:	43/97 - (44%)	Gaps:	6/97 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KCHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHAEHKSVPYCHVPCYGALFGPQLFG 67
            ||..|.|.|||||..|..|..:|..|..|..|.|.|:....|.|....||. .|||..:||:.:|
Human     9 KCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCK-SCYGKKYGPKGYG 72

  Fly    68 HG-----TRVESHKSYGVKGAQKPTGAQANGP 94
            :|     ...:..:|.|:|..:.|.......|
Human    73 YGQGAGTLSTDKGESLGIKHEEAPGHRPTTNP 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785	20/52 (38%)
		UBQ	660..744	CDD:294102
		Nore1-SARAH	762..799	CDD:293125
CSRP1	NP_001180500.1	LIM1_CRP1	8..63	CDD:188863	22/54 (41%)
		Nuclear localization signal. /evidence=ECO:0000255	64..69		1/4 (25%)
		LIM2_CRP	119..172	CDD:188787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910