DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rassf and Csrp3

DIOPT Version :9

Sequence 1:	NP_651126.3	Gene:	Rassf / 42734	FlyBaseID:	FBgn0039055	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_476485.2	Gene:	Csrp3 / 117505	RGDID:	71092	Length:	194	Species:	Rattus norvegicus

Alignment Length:	94	Identity:	34/94 - (36%)
Similarity:	45/94 - (47%)	Gaps:	6/94 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KCHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHAEHKSVPYCHVPCYGALFGPQLFG 67
            ||..|.|.||.||..|..|..:|..|..|..|.|.|:....|.|:|..||.| |||..:||:..|
  Rat     9 KCGACDKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKV-CYGRKYGPKGIG 72

  Fly    68 HG-----TRVESHKSYGVKGAQKPTGAQA 91
            .|     ...::.:..|::..|.|..|:|
  Rat    73 FGQGAGCLSTDTGEHLGLQFQQSPKPARA 101

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785	21/52 (40%)
		UBQ	660..744	CDD:294102
		Nore1-SARAH	762..799	CDD:293125
Csrp3	NP_476485.2	Interaction with TCAP. /evidence=ECO:0000250\|UniProtKB:P50461	1..5
		LIM1_CRP3	9..62	CDD:188865	22/53 (42%)
		Nuclear localization signal. /evidence=ECO:0000255, ECO:0000305\|PubMed:19376126	64..69		1/4 (25%)
		Interaction with CLF2. /evidence=ECO:0000250\|UniProtKB:P50461	94..105		4/8 (50%)
		LIM2_CRP3	120..173	CDD:188866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810