Protein Alignment Rassf and mical3

DIOPT Version :9

• Sequence 1: NP_651126.3
• Gene: Rassf / 42734
• FlyBaseID: FBgn0039055
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_031754432.1
• Gene: mical3 / 100486205
• XenbaseID: XB-GENE-996271
• Length: 2242
• Species: Xenopus tropicalis
• Alignment Length: 1033
• Identity: 206/1033 - (19%)
• Similarity: 314/1033 - (30%)
• Gaps: 381/1033 - (36%)

  Fly     4 CHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHA-----------EHKSVPYCH---- 53
            |:.|.:.||..||..:.|..:|..|.:|:.|...|....:|           .|    ||:
 Frog   904 CYFCRRRVYVMERLSAEGKFFHRSCFKCDYCSTTLRLSCYAYDLEDGKFYCKPH----YCYRRSG 964

  Fly    54 -----VPCYGALFGPQLFGHGTR-VESHKSYGVKG---------AQKPTGAQANGPPLPRDHLES 103
                 .|...||.|.::    || ||.......:|         |:|..|...||   ..||..:
 Frog   965 YSQRKRPAMPALSGKEV----TRTVEDTPDAEDQGRAPLLPAPAAEKTPGPSVNG---VEDHSAA 1022

  Fly   104 KLKVYNQFYDNKSLEIRSREVNNRLVLEGALRVYWGVQGVIHLKEDDDQRI------------LV 156
            |               |.|....|:.||...         :.|::::.:.:            |:
 Frog  1023 K---------------RLRATPERIELENYR---------VSLQKEELEEVPEETLAEHNLSSLL 1063

  Fly   157 RKRNSCRVSKAANESSSDKENEASE------SLAPPT-----------TTTAEVDQLSTDVSLSE 204
            .|.....|:.:::||..::|.:..|      ...||:           ...|::.....||   |
 Frog  1064 DKGEVEEVASSSSESEMEEEEDEEEEEEEPGECLPPSDLGGVPWKEAVKIHAKLKGQDIDV---E 1125

  Fly   205 SMTFDSCSLNEISELPTTPEDASANTTANSKEQTNGNVCN--------------DDEDTTTTDSS 255
            .:.......:|..|.....||........|.|:  |..|.              .||||.....:
 Frog  1126 VVGTQGAGGSEEEEEEEEEEDEEEEDEEVSSEE--GEYCPWERELQQGLWIQRISDEDTVGIFKA 1188

  Fly   256 GTL-------------VEAPTASTSC----------------VSSTLPSKLDRL----------- 280
            |.|             ::|....|..                ||.:.|||...|
 Frog  1189 GNLRLQQALSPVDPTEIKADVRWTHVREVKEERRGSKEERGEVSMSSPSKARHLHSHRHDPVRAW 1253

  Fly   281 ----------------EKL--------------------DWDDIDDLLQVERRHNDKDRIYETMP 309
                            |:|                    |.|||....:.|.|.....|    ..
 Frog  1254 LESVSGATGEYEEGEEEELGTCLAQAEAAGDGDTSADLGDDDDIPSDAEAEERLQQSQR----FK 1314

  Fly   310 VKLPSSQ------------SSSDSSPSKT---------STETTTTTESSSTQSASTNTSST---- 349
            :||..:|            :.|:|.||..         |...|...|:......|....::
 Frog  1315 LKLDVAQEPKVEQPVLPAIADSESVPSPVSLAPKAPVLSPRRTLKAEAEKVPVMSPKAVTSPGGR 1379

  Fly   350 ---DDFMTATGSLTANTNTQNTTTVSTTETSLDNFETCDDAT--------LKPIDFEDFKRSVHQ 403
               |.::....|..|....:..|.:|         ..|....        ..|:.......:...
 Frog  1380 FFADPYLPLDSSNKALVEAKTPTPLS---------PVCSQPVPSQEPVIPTSPVKSPSVPANTRP 1435

  Fly   404 DYVNGANSFTEP---NEGTLK-------RNQ--PIDPSRIHDSLKLYGE--NSAMSKSFNCEHAL 454
            .....|...::|   :||||.       |.|  |:.||.....|...|.  .|....|.|.:..|
 Frog  1436 LISPSAPICSQPLPSSEGTLNATDRPPVRQQPSPLIPSTSLTKLPFTGHVMGSEQLVSPNAKEVL 1500

  Fly   455 RSIDPTLIND----TMNLRSSVG-SPHSAQRQYALQKSGSATVTSRDQ---KKPYQQGRQLFEKG 511
            :.||  ||.:    :..:|.|:| :|....|.:.:.....|:...:.|   .||.:|
 Frog  1501 KRID--LIEEFWTKSAEIRRSLGLAPVDRDRVHEISFPALASTPLQPQAPKSKPEEQ-------- 1555

  Fly   512 INRSKSGPSCFVYSDSDDDDEATLRPQRMATIRRSDIPQRYIQIQM-----DCYPKENVAAASEG 571
                 ..||              |:||::|  ||.: |.| :.|::     ...|.|....:|:|
 Frog  1556 -----KSPS--------------LKPQQVA--RRVN-PSR-LDIELLSPLTPISPSEKELKSSDG 1597

  Fly   572 ESSRADAPSITSGAAA-GDELTQTEDLYTASEGVDGPDGDGSAGLHVTEDGVVLR------RPPR 629
            |....   |.:||... |..:|:|    .|||..:            |.|..:|.      .||.
 Frog  1598 EKKDI---STSSGLGLNGSSITRT----AASESFN------------TSDSAMLTPPSSPPPPPP 1643

  Fly   630 TGASAIKRRSGNRRSRTKLKRRCSINGHYYNRETSF-------FTPPYGSQMSVWVSSM----VT 683
            .|    :..:..|||||..:          |...|.       ..||...:...|..|:    |.
 Frog  1644 QG----EEPATLRRSRTPCQ----------NGPESIPAPALAQSKPPEPKKSPRWEESVRKSFVE 1694

  Fly   684 TTEVINL---VLEKYKVDSSPGNFSLFIVRDNGEQKRLKDDEYPLITRVTLGPHEDVARIFLVDS 745
            :.:.|..   |.:.|  |....|.||        |:|...   |..:||.  ||    ||..  |
 Frog  1695 SVDEIPFADDVEDTY--DERTENSSL--------QERFFT---PPTSRVK--PH----RIGF--S 1738

  Fly   746 RKTDEI--SNEVAQFLNLSLPE-CRAILERYDQEL-AREVA----KIKERYAELRRRI 795
            ::..||  |:|........||: .:...||.::.: |||.:    .:|:..|:.|.::
 Frog  1739 KENGEIPSSSERVHHRKRLLPDVTQEAKERAEERMKAREKSVKSQALKDAIAQQRHKM 1796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rassf	NP_651126.3	LIM_TLP_like	4..57	CDD:188785	17/72 (24%)
		UBQ	660..744	CDD:294102	23/97 (24%)
		Nore1-SARAH	762..799	CDD:293125	10/40 (25%)
mical3	XP_031754432.1	UbiH	87..>226	CDD:357568
		CH_MICAL3	514..624	CDD:409100
		LIM_Mical	904..958	CDD:188823	14/57 (25%)
		PHA03247	1222..>1479	CDD:223021	44/269 (16%)
		Herpes_BLLF1	<1358..1622	CDD:282904	63/312 (20%)
		DUF3585	2055..2220	CDD:403377

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910