Protein Alignment Cow and Spock3

DIOPT Version :9

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_006509579.1
• Gene: Spock3 / 72902
• MGIID: 1920152
• Length: 452
• Species: Mus musculus
• Alignment Length: 626
• Identity: 131/626 - (20%)
• Similarity: 196/626 - (31%)
• Gaps: 284/626 - (45%)

  Fly    32 KYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSK 96
            :|..|.|...:|.||:..:.....|.|:......||:.|.|....|.:.::|:.:|..:|:|:|.
Mouse    66 QYDKEVGQWNKFRDEVEDDYFRTWNPGKPFDQALDPAKDPCLKTKCSRHKVCITQDAQTALCISH 130

  Fly    97 KELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQA 161
            :.|..:..|:                                       |||
Mouse   131 RRLTHSMKEV---------------------------------------GGS------------- 143

  Fly   162 SVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELD 226
                                                     .:|....|::
Mouse   144 -----------------------------------------HKQWRGLPSS-------------- 153

  Fly   227 NCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNN 291
            .|||||:|..:.:||:|..:|||.|:|:|..|:....|.|.|:|.|||.
Mouse   154 TCKPCPIAYASPVCGSDGHSYSSQCKLEYQACVLGKQISIKCEGRCPCP---------------- 202

  Fly   292 KYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHN 356
                                             ::..||.|
Mouse   203 ---------------------------------SDKSMNIG------------------------ 210

  Fly   357 NHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAY 421
                                                      ||....
Mouse   211 ------------------------------------------RNVKRA----------------- 216

  Fly   422 PSKSAECKPQQLTAIGNRLLDWFSVIM---ADSKKRRQHSQKSKAHFP----PACKTEAKWMFGH 479
                  |...:...:.|||.|||..:.   :.:||.:...:..::.|.    |.||....|||..
Mouse   217 ------CSDLEFREVANRLRDWFKALHESGSQNKKTKALLRPERSRFDTSILPICKDSLGWMFNR 275

  Fly   480 LDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEK-TDRPC----AAV 539
            ||.|.|..|...|:..:..|:||:|.|.|.::||...||.|:..|||.||:: .|.||    :.:
Mouse   276 LDTNYDLLLDQSELGSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCHTELSNI 340

  Fly   540 RRRIAGDFAGEIGAYAPDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNC------- 597
            ::|  ......:|.|.|.||..|:|||||||.|||.|||||::|.|...:|..|..:|
Mouse   341 QKR--QGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVADCAIDFEIS 403

  Fly   598 ------------------ESVVNNAASLTSDDEDEGADDED 620
                              :.::|:...:..||||||.||:|
Mouse   404 GDFASGDFREWTDDEGEEDDIMNDKDDIEDDDEDEGDDDDD 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	14/31 (45%)
		SPARC_EC	427..539	CDD:238155	41/123 (33%)
		SPARC_Ca_bdg	427..526	CDD:287550	34/105 (32%)
		TY	535..597	CDD:238114	28/65 (43%)
Spock3	XP_006509579.1	Kazal_2	153..201	CDD:369449	21/61 (34%)
		EFh_SPARC_TICN3	217..329	CDD:320018	38/111 (34%)
		EF-hand motif	265..296	CDD:320018	11/30 (37%)
		EF-hand motif	297..327	CDD:320018	15/29 (52%)
		TY	332..396	CDD:238114	28/65 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839431
Domainoid	1	1.000	74	1.000	Domainoid score	I9094
eggNOG	1	0.900	-	-		E1_KOG3555
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I3399
Isobase	1	0.950	-	0	Normalized mean entropy	S6033
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002140
OrthoInspector	1	1.000	-	-		otm43625
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5366
SonicParanoid	1	1.000	-	-		X1424
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.730