Protein Alignment Cow and cracdlb

DIOPT Version :10

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_005160178.1
• Gene: cracdlb / 571514
• ZFINID: ZDB-GENE-090313-40
• Length: 832
• Species: Danio rerio
• Alignment Length: 702
• Identity: 116/702 - (16%)
• Similarity: 228/702 - (32%)
• Gaps: 261/702 - (37%)

  Fly    98 ELHKNRDEIITKAKYLEEEAKRR----VNQQDNQ----DSQDAEDINNDDE----DNSSD----- 145
            ::.||.:|:..:.|...::.|.|    :.:::::    .||.|.|||..|.    |:|.|
Zfish     7 DMDKNAEELTGRKKSRFKQLKTRLFGKLKKKESEGLIKQSQSASDINAPDSRRGGDDSEDEFTYP 71

  Fly   146 -GGS----SNSSPTGTNNAQAS----VQGNEETDDEDKSLSL---------------------GD 180
             |.|    |:.|...|:..|::    |...|....:.|:|.|                     .|
Zfish    72 QGLSPRALSHDSIFFTDQTQSTEPTRVLSQENVHGKIKALQLKLQQQNLHLGPPPMLIPGKRTED 136

  Fly   181 DDESKEDD---------VFYEN-------------------SIA-AGDKQQQQQQLSQPAAGP-S 215
            ...:.|||         ..||.                   |:| .|.::::|..|.|.::.| |
Zfish   137 SGATSEDDGLPCSPPETYLYERVMHGGIYKYPEPRKHLSSLSLAGTGSEEEEQGDLFQSSSRPLS 201

  Fly   216 VIQQDDDEELDNCKPCPVAKPTFLCGAD-NRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVD 279
            .:.:...:.: .|....:|.||  .|.| :...|....||.....|..|::
Zfish   202 PVFKPSSQSI-ICSSSSLATPT--VGVDFSSPASYTATLDNSAAHHRMSVK-------------- 249

  Fly   280 GKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNT 344
             .|.||.|...|: ...:|:..:::.:                               :.:|.::
Zfish   250 -PRNQRASTRGNR-GPAVSISPRKRSE-------------------------------SISDLDS 281

  Fly   345 IMNDKEDNN---------------RHNNH------INAQYTF-----TPEEIKYDNKHYKYLKYT 383
            |:::|:|::               .|.:|      |..:.|.     ||.:|:
Zfish   282 ILSEKDDDDDDEVDDEIMTSTETVHHLSHSPPTVEIKVETTIPEAPETPVQIQ------------ 334

  Fly   384 AYKKDSKYQEDKHKMRNYN------EVVEKQQQ-----KFNKNS-NLNAYPSKSAECKPQQLTAI 436
                    :||:.|:...:      |:::.|:.     |...|. .|...|..|....|..|..:
Zfish   335 --------EEDEEKLSTPHLTPLSAEILKSQESLEPEGKLTMNPLYLQPMPFGSGPPSPSGLPEV 391

  Fly   437 GNRLLDWFSVIMAD--------SKKRRQHSQKSKAH---------------FPPACKTEAKWMF- 477
              .|::..|.|..|        :|:..:....::.|               .||:.|...:.:.
Zfish   392 --HLIEAESFIQKDGMHDIQIVAKESMKEEPSTRFHPVPLPRAKKPKVEIKSPPSPKASTESVSL 454

  Fly   478 --------GHLDLNNDGQL--------------SLQEMYDLEHD---------QNERCIKPFIDT 511
                    .....|||..|              :|:.:.|.|.:         :.::.|:...||
Zfish   455 QFLLASAKNRSKTNNDATLNEGDLKMKMQTINSNLEVLKDEEKETKPVENLLYRMQKSIEKIEDT 519

  Fly   512 CDLDTDSSINTREWCRCFEKTDRPCAAVRRRIA-GDFAGEIGAYAPDCDIQGFYKPTQCHNSVGV 575
            ..:                :.:.|...|..::| |....::.:...:.|.:...:|.:..::.||
Zfish   520 KSI----------------RREAPAPPVMSKLAPGTNGKKVDSPTENVDSEKQEEPEERRSAFGV 568

  Fly   576 CWCVDKHGVEFANTRTRGKPNCESVVNNAASLTSDDEDEGADDEDSAEGSAD 627
            ........:::.:..:|.|...:.....::::.:|.| |.|...:...|::|
Zfish   569 HLRTTSLSLKYRSEVSRMKDETKRYSLESSTVLADSE-EHAGKAEVFRGASD 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	7/32 (22%)
		EFh_SPARC_TICN	428..533	CDD:320011	21/159 (13%)
		EF-hand motif	469..500	CDD:320011	8/62 (13%)
		EF-hand motif	501..533	CDD:320011	3/31 (10%)
		TY	535..597	CDD:238114	10/62 (16%)
cracdlb	XP_005160178.1	DUF4592	123..258	CDD:464602	29/152 (19%)
		PRK13914	<597..>782	CDD:237555	6/24 (25%)