Protein Alignment Cow and spock3

DIOPT Version :10

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001314916.1
• Gene: spock3 / 562002
• ZFINID: ZDB-GENE-090311-24
• Length: 387
• Species: Danio rerio
• Alignment Length: 646
• Identity: 138/646 - (21%)
• Similarity: 204/646 - (31%)
• Gaps: 294/646 - (45%)

  Fly    12 LALVLMSSSLIGSTEARNKK------KYVGETGGDFEFIDEINK-NTQSNKNLGEHKRWIHDPSS 69
            |.||.:.:.||....|||..      |::  ||...:|.||:.: .|.|.   |:......||:.
Zfish     2 LVLVGVCALLIAGASARNDNGNFLDDKWL--TGRWDKFRDEVEEPGTWSP---GKPFDQALDPAK 61

  Fly    70 DLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAED 134
            |.|..:.|.:.::|:.||..:..|||                      :||::.:|
Zfish    62 DPCLKIKCGRHKVCVAEDYQTPTCVS----------------------QRRMSFKD--------- 95

  Fly   135 INNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGD 199
                                                                             
Zfish    96 ----------------------------------------------------------------- 95

  Fly   200 KQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSI 264
                 ..|:.|              |..||.|||..|:.:||.|..|||:.|:|:|..||....|
Zfish    96 -----MNLNSP--------------LLKCKRCPVVHPSPICGTDGHTYSTKCKLEYQACISGKQI 141

  Fly   265 RIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMM 329
            .:.|.|.|||..
Zfish   142 SVKCPGQCPCAP----------------------------------------------------- 153

  Fly   330 NSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQED 394
                   ||
Zfish   154 -------GN-------------------------------------------------------- 155

  Fly   395 KHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMAD---SKKRRQ 456
                                       |::..||...::|.:.:||.:|.:|:...   :||.:.
Zfish   156 ---------------------------PAEKRECGNAEMTEVVSRLREWITVLHESGNTNKKYKF 193

  Fly   457 HSQKSKAHFP--PACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSS 519
            ...:.|....  |.||....|||..||.|.|..|...|:..|..::::.|.|.|:.:||.:.|..
Zfish   194 QKPEKKVDMSKVPLCKDSLGWMFSRLDTNFDLHLDQSELSSLNSEKSDVCTKAFLRSCDPNRDRL 258

  Fly   520 INTREWCRCFEK-TDRPCAAVRRRIAGDFAGE--IGAYAPDCDIQGFYKPTQCHNSVGVCWCVDK 581
            ::::|||.||:: .:.||.:....|....||:  :|.|.|.||..|||:|.|||.|.|.|||||:
Zfish   259 VSSQEWCSCFQRYQEAPCQSEITIIHKQQAGKKLLGPYVPSCDEDGFYRPQQCHGSSGQCWCVDR 323

  Fly   582 HGVEFANTRTRGKPNCESVVNNAA------SLTSDDED--------EGADDEDSAEGSADQ 628
            :|.|.|.:.|.|...|  ||.::.      ||.|||||        |..||:|..:.:.|:
Zfish   324 YGNELAGSHTHGPAEC--VVESSGDFGSGDSLLSDDEDGDVVNDEEEMGDDDDEYDQADDE 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	14/31 (45%)
		EFh_SPARC_TICN	428..533	CDD:320011	33/110 (30%)
		EF-hand motif	469..500	CDD:320011	12/30 (40%)
		EF-hand motif	501..533	CDD:320011	11/32 (34%)
		TY	535..597	CDD:238114	29/63 (46%)
spock3	NP_001314916.1	KAZAL	106..149	CDD:197624	19/42 (45%)
		EFh_SPARC_TICN	162..272	CDD:320011	33/109 (30%)
		EF-hand motif	208..239	CDD:320011	12/30 (40%)
		EF-hand motif	240..272	CDD:320011	11/31 (35%)
		Thyroglobulin_1	276..339	CDD:459665	28/62 (45%)