Protein Alignment Cow and Spock1

DIOPT Version :9

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_038951544.1
• Gene: Spock1 / 306759
• RGDID: 1311496
• Length: 444
• Species: Rattus norvegicus
• Alignment Length: 660
• Identity: 139/660 - (21%)
• Similarity: 208/660 - (31%)
• Gaps: 293/660 - (44%)

  Fly     6 LIASACL--ALVLMSSSLIGSTEARNKKKYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPS 68
            |...|.|  |..|.:...:.:....::.||......:.|  |:..:|...||...:    ..|||
  Rat    27 LAGGAALNNANFLDNDQWLSTVSQYDRDKYWNRFRDEVE--DDYFRNWNPNKPFDQ----ALDPS 85

  Fly    69 SDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAE 133
            .|.|..:.|...::|:.:|..:|:|||:|.|...:
  Rat    86 KDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQ------------------------------ 120

  Fly   134 DINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAG 198
                                                               |:..|.:::.:
  Rat   121 ---------------------------------------------------KKGSVAHKHWV--- 131

  Fly   199 DKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTS 263
                          |||        .|..|||||||:...:||:|..||:|.|:|::|.|....|
  Rat   132 --------------GPS--------NLVKCKPCPVAQSAMVCGSDGHTYTSKCKLEFHACSTGKS 174

  Fly   264 IRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIM 328
            :...|.|.|||                        |.:.:.:.|:.:.:
  Rat   175 LSSLCDGPCPC------------------------LPEPEPEPQKPKAE---------------- 199

  Fly   329 MNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQE 393
                                                                             
  Rat   200 ----------------------------------------------------------------- 199

  Fly   394 DKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMADSKK--RRQ 456
                                          ||| |..::|..:.:||.|||..:..|:.:  :..
  Rat   200 ------------------------------KSA-CTDKELRNLASRLKDWFGALHEDANRVIKPT 233

  Fly   457 HSQKSKAHFP----PACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTD 517
            .|..::..|.    |.||....|||..||:|.|..|...|:..:..|:.|.||||..::||...|
  Rat   234 SSDTTQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDHSEINAIYLDKYEPCIKPLFNSCDSFKD 298

  Fly   518 SSINTREWCRCFEKT-DRPCAAVRRRIAGDFAGE--IGAYAPDCDIQGFYKPTQCHNSVGVCWCV 579
            ..::..|||.||:|. ..||.....||.....|:  :||:.|.|:.:|:||.||||.|.|.||||
  Rat   299 GKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCV 363

  Fly   580 DKHGVEFANTRTRGKPNCE-------------SVV---------------------NNAASLTSD 610
            ||:|.|.|.:|.:|..:||             |||                     .:..::..|
  Rat   364 DKYGNELAGSRKQGTVSCEEEQETSGDFGSGGSVVLLDDLDDERELGPKDKEGKLRVHTRAVRED 428

  Fly   611 DEDEGADDED 620
            ||||..|.||
  Rat   429 DEDEDDDKED 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	13/31 (42%)
		SPARC_EC	427..539	CDD:238155	39/118 (33%)
		SPARC_Ca_bdg	427..526	CDD:287550	32/104 (31%)
		TY	535..597	CDD:238114	29/63 (46%)
Spock1	XP_038951544.1	Kazal_2	139..>176	CDD:400135	18/36 (50%)
		EFh_SPARC_EC	203..314	CDD:330171	37/110 (34%)
		EF-hand motif	250..281	CDD:320009	11/30 (37%)
		EF-hand motif	282..314	CDD:320009	14/31 (45%)
		TY	317..378	CDD:238114	28/60 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343249
Domainoid	1	1.000	75	1.000	Domainoid score	I8825
eggNOG	1	0.900	-	-		E1_KOG3555
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3259
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1235834at2759
OrthoFinder	1	1.000	-	-		FOG0002140
OrthoInspector	1	1.000	-	-		otm45701
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12352
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1424
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.860