Protein Alignment Cow and Spock1

DIOPT Version :10

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001258226.1
• Gene: Spock1 / 306759
• RGDID: 1311496
• Length: 441
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 131/619 - (21%)
• Similarity: 194/619 - (31%)
• Gaps: 289/619 - (46%)

  Fly    45 DEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITK 109
            |:..:|...||...:    ..|||.|.|..:.|...::|:.:|..:|:|||:|.|...:
  Rat    63 DDYFRNWNPNKPFDQ----ALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQ------ 117

  Fly   110 AKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDK 174
                                                                             
  Rat   118 ----------------------------------------------------------------- 117

  Fly   175 SLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFL 239
                      |:..|.:::.:                 |||        .|..|||||||:...:
  Rat   118 ----------KKGSVAHKHWV-----------------GPS--------NLVKCKPCPVAQSAMV 147

  Fly   240 CGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQ 304
            ||:|..||:|.|:|::|.|....|:...|.|.|||                        |.:.:.
  Rat   148 CGSDGHTYTSKCKLEFHACSTGKSLSSLCDGPCPC------------------------LPEPEP 188

  Fly   305 QQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEE 369
            :.|:.:.:
  Rat   189 EPQKPKAE--------------------------------------------------------- 196

  Fly   370 IKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLT 434
                                                                  ||| |..::|.
  Rat   197 ------------------------------------------------------KSA-CTDKELR 206

  Fly   435 AIGNRLLDWFSVIMADSKK--RRQHSQKSKAHFP----PACKTEAKWMFGHLDLNNDGQLSLQEM 493
            .:.:||.|||..:..|:.:  :...|..::..|.    |.||....|||..||:|.|..|...|:
  Rat   207 NLASRLKDWFGALHEDANRVIKPTSSDTTQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDHSEI 271

  Fly   494 YDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKT-DRPCAAVRRRIAGDFAGE--IGAYA 555
            ..:..|:.|.||||..::||...|..::..|||.||:|. ..||.....||.....|:  :||:.
  Rat   272 NAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFI 336

  Fly   556 PDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCE-------------SVV------ 601
            |.|:.:|:||.||||.|.|.||||||:|.|.|.:|.:|..:||             |||
  Rat   337 PRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGTVSCEEEQETSGDFGSGGSVVLLDDLD 401

  Fly   602 ---------------NNAASLTSDDEDEGADDED 620
                           .:..::..|||||..|.||
  Rat   402 DERELGPKDKEGKLRVHTRAVREDDEDEDDDKED 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	13/31 (42%)
		EFh_SPARC_TICN	428..533	CDD:320011	37/111 (33%)
		EF-hand motif	469..500	CDD:320011	11/30 (37%)
		EF-hand motif	501..533	CDD:320011	14/32 (44%)
		TY	535..597	CDD:238114	29/63 (46%)
Spock1	NP_001258226.1	Kazal_2	136..>173	CDD:400135	18/36 (50%)
		EFh_SPARC_EC	200..311	CDD:330171	37/110 (34%)
		EF-hand motif	247..278	CDD:320009	11/30 (37%)
		EF-hand motif	279..309	CDD:320009	13/29 (45%)
		TY	314..375	CDD:238114	28/60 (47%)