Protein Alignment Cow and Cd74

DIOPT Version :10

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001036070.1
• Gene: Cd74 / 16149
• MGIID: 96534
• Length: 279
• Species: Mus musculus
• Alignment Length: 262
• Identity: 59/262 - (22%)
• Similarity: 100/262 - (38%)
• Gaps: 66/262 - (25%)

  Fly   382 YTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKP----QQLTAIGNRLLD 442
            |..|::..:.  ||..:.:.|..:|..:.|..|::            ||    :..|.:..|.:.
Mouse    52 YFLYQQQGRL--DKLTITSQNLQLESLRMKLPKSA------------KPVSQMRMATPLLMRPMS 102

  Fly   443 WFSVIMADSKKRRQHSQKSKAHFPPACKTEAKWMFGHLDLNNDGQLSLQEM-----YDLEHDQN- 501
            ..::::...|...::...::.|..            || |...|.|...::     .:|:|.:|
Mouse   103 MDNMLLGPVKNVTKYGNMTQDHVM------------HL-LTRSGPLEYPQLKGTFPENLKHLKNS 154

  Fly   502 ---------ERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAGEIGAYAPD 557
                     |..:|.:     |..:.|.|:.|..:..|...:.....:..::...|...||:.|.
Mouse   155 MDGVNWKIFESWMKQW-----LLFEMSKNSLEEKKPTEAPPKVLTKCQEEVSHIPAVYPGAFRPK 214

  Fly   558 CDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTSDDEDEGADDEDSA 622
            ||..|.|.|.|||.|.|.||||..:|.|..:|::||:.||               .|..|.||.:
Mouse   215 CDENGNYLPLQCHGSTGYCWCVFPNGTEVPHTKSRGRHNC---------------SEPLDMEDLS 264

  Fly   623 EG 624
            .|
Mouse   265 SG 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624
		EFh_SPARC_TICN	428..533	CDD:320011	21/123 (17%)
		EF-hand motif	469..500	CDD:320011	7/35 (20%)
		EF-hand motif	501..533	CDD:320011	8/41 (20%)
		TY	535..597	CDD:238114	23/61 (38%)
Cd74	NP_001036070.1	MHC2-interact	1..112	CDD:462750	12/73 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		MHCassoc_trimer	119..184	CDD:462614	15/82 (18%)
		TY	195..254	CDD:238114	23/58 (40%)