Protein Alignment Cow and spock2

DIOPT Version :10

• Sequence 1: NP_001262857.1
• Gene: Cow / 42733
• FlyBaseID: FBgn0039054
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_012821500.1
• Gene: spock2 / 100144943
• XenbaseID: XB-GENE-1003767
• Length: 422
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 133/664 - (20%)
• Similarity: 202/664 - (30%)
• Gaps: 300/664 - (45%)

  Fly    10 ACLALVLMSSSLIGSTEARNKKKYVGETGG---DFEFIDEINKNTQSNKNLGEHKRWIH------ 65
            :||.|:.:   |:....|:...|.|..||.   |.:::..||:.:      |:.|.|..
 Frog     7 SCLILLPL---LLPIAWAQGDGKEVENTGNFMEDEQWLSSINQYS------GKIKHWNRFRDEVE 62

  Fly    66 -----------------DPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYL 113
                             |.:.|.|:.:.|.:.::|:......|:|:|:|:|
 Frog    63 DDYIKSWEDNQPGDEALDTTKDPCQKVKCSRHKVCIAHGYQKAMCISRKKL-------------- 113

  Fly   114 EEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSL 178
                :.|:.|                                   ....:.||.:        ||
 Frog   114 ----EHRIKQ-----------------------------------PSMKIHGNRD--------SL 131

  Fly   179 GDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGAD 243
                                                             ||||.|.:|..:||:|
 Frog   132 -------------------------------------------------CKPCHVTQPAAVCGSD 147

  Fly   244 NRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQ 308
            ..||||:|:|:...|:.|..:.:.|:|.|||.
 Frog   148 GHTYSSVCKLEQQACLSSKQLTVKCQGSCPCP--------------------------------- 179

  Fly   309 QQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYD 373
                                                           ..|       ||
 Frog   180 -----------------------------------------------TEH-------TP------ 184

  Fly   374 NKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGN 438
                     |...:..|..|                                 .|..|.|..:|:
 Frog   185 ---------TTTTETGKQGE---------------------------------TCTGQDLADLGD 207

  Fly   439 RLLDWFSVIMADSKKRRQHSQKSK------AHFPPACKTEAKWMFGHLDLNNDGQLSLQEMYDLE 497
            ||.|||.::..:||:....:..||      ......||....|||..||.|||..|...|:..:.
 Frog   208 RLRDWFQLLHENSKQNNTSNPGSKQVNVLDKSLVAGCKDSIGWMFSKLDSNNDLFLDQAELAAIN 272

  Fly   498 HDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAG--EIGAYAPDCDI 560
            .|:.|.||:||.::||...|..::|.|||.||.:...||.....::....|.  :.|.:.|.||.
 Frog   273 LDKYEICIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLVELEKVQIQEAAKRKPGVFIPSCDE 337

  Fly   561 QGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTS------------DDED 613
            .|:|:..||..:.|.|||||:||.|...||..|.|:|:.:|..:....|            :|..
 Frog   338 DGYYRKMQCDQASGECWCVDQHGSELTGTRIHGNPDCDDMVGFSGDFGSGVGWEDEEEKETEDAG 402

  Fly   614 EGADDEDSAEGSAD 627
            |.|::|:...|.||
 Frog   403 EEAEEEEGETGEAD 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cow	NP_001262857.1	KAZAL	<240..272	CDD:197624	13/31 (42%)
		EFh_SPARC_TICN	428..533	CDD:320011	40/110 (36%)
		EF-hand motif	469..500	CDD:320011	12/30 (40%)
		EF-hand motif	501..533	CDD:320011	14/31 (45%)
		TY	535..597	CDD:238114	24/63 (38%)
spock2	XP_012821500.1	KAZAL	<143..176	CDD:197624	13/32 (41%)
		EFh_SPARC_TICN2	197..308	CDD:320017	40/110 (36%)
		EF-hand motif	244..275	CDD:320017	12/30 (40%)
		EF-hand motif	276..308	CDD:320017	14/31 (45%)
		Thyroglobulin_1	311..374	CDD:459665	23/62 (37%)