Protein Alignment CG6738 and ACY1

DIOPT Version :10

• Sequence 1: NP_651124.1
• Gene: CG6738 / 42732
• FlyBaseID: FBgn0039053
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_000657.1
• Gene: ACY1 / 95
• HGNCID: 177
• Length: 408
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 177/398 - (44%)
• Similarity: 248/398 - (62%)
• Gaps: 7/398 - (1%)

  Fly     7 EKNEEIRIFREYLRIPSVHPNIDYTACVEFIKRQADSLNL---PVEVVFPAVKSKPVVIIKWEGS 68
            |::..:.:||:||||.:|.|..||.|.|.|.:..|..|.|   .|||....|    |.::.|.|:
Human     8 EEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYV----VTVLTWPGT 68

  Fly    69 QPKLPSIILSSHMDVVPVFPEMWTHEPFSADIDEEGRIFARGAQDMKSVGTQYLGAIRLLRADGF 133
            .|.|.||:|:||.||||||.|.|:|:||.|..|.||.|:||||||||.|..|||.|:|.|:.:|.
Human    69 NPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGH 133

  Fly   134 QPKRTLYVTFVPDEEIGGIHGMAAFVETDFYKQMNVGFSLDEGGTSASDVHHLFYAERIRWILKL 198
            :..||:::|||||||:||..||..||:...:..:..||:||||..:.:|...:||:||..|.:::
Human   134 RFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSERSPWWVRV 198

  Fly   199 KVAGTAGHGSLLLPDTAGVKLNYVLNKLTEFRESQIQRLKNDKSLSIGDVTTVNLTQLSGGVQSN 263
            ...|..||.|..:.|||..||:.|:|.:..|||.:.|||:::..|..|.||:||||:|.|||..|
Human   199 TSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYN 263

  Fly   264 VVPPLFEAIFDIRLAITLDLVAFEREIRNWCEEAGGGIDIEFPLKEAYVAATRLDDSNPYWLALK 328
            |:|....|.||.|:|..:|..|||.::::||:.||.|:.:||..|..:...|..|||||:|.|..
Human   264 VIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQKWMHPQVTPTDDSNPWWAAFS 328

  Fly   329 VALDELGLKVKPIVCFAVTDCRFIRQQGTPAIGFSPIINTTVLIHDHDEFLRADDYLNGIQVYKK 393
            ....::.|.::|.:..|.||.|:||..|.||:||||:..|.||:|||||.|....:|.|:.:|.:
Human   329 RVCKDMNLTLEPEIMPAATDNRYIRAVGVPALGFSPMNRTPVLLHDHDERLHEAVFLRGVDIYTR 393

  Fly   394 IIPNLTEV 401
            ::|.|..|
Human   394 LLPALASV 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6738	NP_651124.1	M20_AcylaseI_like	9..398	CDD:349898	174/391 (45%)
ACY1	NP_000657.1	M20_AcylaseI_like	9..399	CDD:349898	174/393 (44%)