DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6733 and acy1

DIOPT Version :9

Sequence 1:	NP_651123.1	Gene:	CG6733 / 42731	FlyBaseID:	FBgn0039052	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_009294786.1	Gene:	acy1 / 393970	ZFINID:	ZDB-GENE-040426-755	Length:	427	Species:	Danio rerio

Alignment Length:	390	Identity:	185/390 - (47%)
Similarity:	253/390 - (64%)	Gaps:	1/390 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IKIFREYLRIPTVHPDVDYTACVEFLKRQASSLNLPVEVVYPAVQTKPVVIIKWEGSQPELSSIV 76
            :.:||||||:.||||:.||.|.::||:|.|..|.||::.| .....:.|.||.|.||:|||.|:|
Zfish    32 VTLFREYLRLKTVHPEPDYDAALKFLERMAEELALPMKKV-EVCPGRVVAIISWIGSRPELKSVV 95

  Fly    77 LNSHTDVVPVFREKWTHEPFSADIDEEGRIFARGTQDMKSVGTQYLGAIRLLKASGFKPKRNLYV 141
            ||||||||||:.|.|.|.||:|..|.:|.|:|||.||||||..||:.|||.|||:|.:..|.:::
Zfish    96 LNSHTDVVPVYEEHWKHHPFAAVKDADGNIYARGAQDMKSVTIQYIEAIRRLKAAGKRFSRTIHL 160

  Fly   142 TFVPDEETGGHLGMAEFVKTDYYKKMNAGFSLDEGATSESDVHHLFYAERLRWGLKLKVSGTSGH 206
            |||||||.|||.||..|||...::|:|.||:||||..:.::.:.:||.||..|.:.::..|:.||
Zfish   161 TFVPDEEVGGHKGMETFVKHPEFQKLNMGFALDEGLANPTNAYTVFYGERNPWWITVRCPGSPGH 225

  Fly   207 GSLLLPNTAGVKLNYLVNKLTEFRTSQVENLARDSSLSKGDVTTVNLTQLSGGVQSNVVPPLFEA 271
            ||..:.|||..||..::|...|||..:.:.|......:.|||||:|:|.:.|||..||||...:.
Zfish   226 GSRFVENTAAEKLRRVINSFLEFREKEKQRLNTSECFTLGDVTTINMTMVKGGVAYNVVPAEMDV 290

  Fly   272 VFDIRIAITVNVVAFEKQIRDWCEEAGGGIEIDFFQKEPYIGPTKLDNSNPYWLAVKAAIDELGL 336
            .||:||..|||:..||::|:.||.|||..:..||.||......|..|.::|:|.|..:....:.:
Zfish   291 SFDLRIPPTVNLQEFEEKIKVWCREAGEDVTYDFAQKHMDQNLTSTDENDPWWQAFSSTCKAMNM 355

  Fly   337 KVHPIVCPGATDSRFIREKGTPAIGFSPIINTTMRIHDHDEFLQADVYLNGIDVYKKIIRNLAEV 401
            .:...:.|.|||||||||.|.|||||||:..|.:.:|||:|:|...|:|.||.||:::|..||.|
Zfish   356 TLKKEIFPAATDSRFIREVGLPAIGFSPMNLTPILLHDHNEYLNEQVFLQGIQVYERLIPALAGV 420

Fly 402 401
Zfish 421 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6733	NP_651123.1	Ac-peptdase-euk	1..401	CDD:273850	184/388 (47%)
CG6733	NP_651123.1	M20_AcylaseI_like	8..399	CDD:193524	182/386 (47%)
acy1	XP_009294786.1	Ac-peptdase-euk	28..420	CDD:273850	184/388 (47%)
acy1	XP_009294786.1	M20_AcylaseI_like	28..418	CDD:193524	182/386 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582006
Domainoid	1	1.000	336	1.000	Domainoid score	I1081
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110440
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1895
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		otm26566
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	O	PTHR45892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800