DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6733 and C10C5.5

DIOPT Version :9

Sequence 1:	NP_651123.1	Gene:	CG6733 / 42731	FlyBaseID:	FBgn0039052	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_501652.2	Gene:	C10C5.5 / 177769	WormBaseID:	WBGene00007509	Length:	397	Species:	Caenorhabditis elegans

Alignment Length:	403	Identity:	174/403 - (43%)
Similarity:	247/403 - (61%)	Gaps:	16/403 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NNEEIKI--FREYLRIPTVHPDVDYTACVEFLKRQASSLNLPVEVVYPAVQTKP---VVIIKWEG 67
            :.|.|.:  ||||||:.|..|:.:|.||.:||.:.|..|.    :...:::|.|   :||:...|
Worm     2 SEEHIAVTRFREYLRVNTEQPNPNYAACRDFLFKYADELG----IARRSIETAPGVFLVIMTIPG 62

  Fly    68 SQPELSSIVLNSHTDVVPVFREKWTHEPFSADIDEEGRIFARGTQDMKSVGTQYLGAIRLLKASG 132
            |||||.||:|.|||||||.|||.|||:|:||..||:|.|||||.||||.||.|.:.|:|.|.|.|
Worm    63 SQPELPSIMLYSHTDVVPTFREHWTHDPYSAFKDEDGNIFARGAQDMKCVGVQQMEALRNLFAQG 127

  Fly   133 FKP-KRNLYVTFVPDEETGGHLGMAEFVKTDYYKKMNAGFSLDEGATSESDVHHLFYAERLRWGL 196
            .:. ||.:::.:.||||..|..||..|.|||.:||:|.|||||||..|:.||:.:|||||:.|.:
Worm   128 IRQWKRTIHLVWGPDEEIFGINGMKGFAKTDEFKKLNLGFSLDEGMPSDDDVYKVFYAERVAWWV 192

  Fly   197 KLKVSGTSGHGSLLLPNTAGVKLNYLVNKLTEFRTSQVENLARDSSLSKGDVTTVNLTQLSGGVQ 261
            |:...|..||||..:.|||..||...:....:||..|...|..:.:|:.|||||:|:..::||||
Worm   193 KVTFPGNPGHGSQFMENTAMEKLERFLASARKFRNEQKVVLESNPNLTLGDVTTLNVNIVNGGVQ 257

  Fly   262 SNVVPPLFEAVFDIRIAITVNVVAFEKQIRDWCEEAGGGIEIDFFQ---KEPYIGPTKLDNSNPY 323
            .||:|..|||..|:|:....:.....:.:..|.:.||.|:..:|.|   ::|....|: |||  :
Worm   258 FNVIPEKFEAYVDMRLTPHEDFNKIREMLDQWAKNAGEGVTYEFSQYSDQKPISAHTR-DNS--F 319

  Fly   324 WLAVKAAIDELGLKVHPIVCPGATDSRFIREKGTPAIGFSPIINTTMRIHDHDEFLQADVYLNGI 388
            |.|.:.::::...|....:...:|||||:|.:|..:|.|||:|||....|||:|:|...|:|.|:
Worm   320 WAAFEDSLNQENCKFEKGIMVASTDSRFVRYEGVNSINFSPMINTPFLPHDHNEYLNEKVFLRGL 384

  Fly   389 DVYKKIIRNLAEV 401
            ::|:.||.||..|
Worm   385 EIYQTIINNLGNV 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6733	NP_651123.1	Ac-peptdase-euk	1..401	CDD:273850	173/401 (43%)
CG6733	NP_651123.1	M20_AcylaseI_like	8..399	CDD:193524	172/399 (43%)
C10C5.5	NP_501652.2	M20_AcylaseI_like	4..395	CDD:349898	172/397 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160022
Domainoid	1	1.000	290	1.000	Domainoid score	I829
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110440
Inparanoid	1	1.050	332	1.000	Inparanoid score	I1424
Isobase	1	0.950	-	0	Normalized mean entropy	S3343
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		mtm4767
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	O	PTHR45892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750