DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6733 and C06A6.4

DIOPT Version :9

Sequence 1:	NP_651123.1	Gene:	CG6733 / 42731	FlyBaseID:	FBgn0039052	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001021301.1	Gene:	C06A6.4 / 177571	WormBaseID:	WBGene00015509	Length:	411	Species:	Caenorhabditis elegans

Alignment Length:	413	Identity:	179/413 - (43%)
Similarity:	246/413 - (59%)	Gaps:	24/413 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NEEIKI--FREYLRIPTVHPDVDYTACVEFLKRQASSLNLPVEVVYPAVQTKP---VVIIKWEGS 68
            :|:|.:  ||||||:.|..|..||.||.:||.:.|..|.:...    :|:|.|   .||:...||
Worm     2 SEDIGVTRFREYLRVNTEQPKPDYEACRDFLFKYADELGIERR----SVETAPGTYFVIMTIPGS 62

  Fly    69 QPELSSIVLNSHTDVVPVFREKWTHEPFSADIDEEGRIFARGTQDMKSVGTQYLGAIRLLKASGF 133
            :|:|.||:|.|||||||.|||.|||:|:||..||:|.|||||.||||.||.||:.|:|...|.|.
Worm    63 KPDLPSIMLYSHTDVVPTFREYWTHDPYSAFKDEDGNIFARGAQDMKCVGVQYMEALRNWFAKGV 127

  Fly   134 KP-KRNLYVTFVPDEETGGHLGMAEFVKTDYYKKMNAGFSLDEGATSESDVHHLFYAERLRWGLK 197
            |. .|.:::.:.||||.|...||..|..|:.:||:|..|:||||..:|.||:.:|||||:.|.:|
Worm   128 KQWTRTIHIVWGPDEEIGHINGMKGFAVTEEFKKLNIDFALDEGIATEDDVYKIFYAERIPWWVK 192

  Fly   198 LKVSGTSGHGSLLLPNTAGVKLNYLVNKLTEFRTSQVENLARDSSLSKGDVTTVNLTQLSGGVQS 262
            :.:.|..||||..:..||..||:.|:..:.|||..|...||.....:.|||||.|:|.::||||.
Worm   193 VTLPGHPGHGSKFIEKTAIEKLHKLIASVDEFRNEQKSLLAEHPEWTVGDVTTSNITIINGGVQV 257

  Fly   263 NVVPPLFEAVFDIRIAITVNVVAFEKQIRDWCEEAGGGIEIDFFQKEPYIGPTKLD--------- 318
            ||||..|||..|||:....::.|...::..|.:|||.|:..:|.|.......:.:|
Worm   258 NVVPEKFEAYIDIRVTPLQDLDAVLARVDQWAKEAGEGVTYEFMQSTNPADKSTIDFETFSNFKL 322

  Fly   319 -----NSNPYWLAVKAAIDELGLKVHPIVCPGATDSRFIREKGTPAIGFSPIINTTMRIHDHDEF 378
                 ..:|:|.|:..|:.:.|.|....:..|||||||:|.:|..||||||||||...:|||:||
Worm   323 ISPNTREDPFWAAIDDALQKEGCKYKKEIFIGATDSRFVRAQGIRAIGFSPIINTPSLLHDHNEF 387

  Fly   379 LQADVYLNGIDVYKKIIRNLAEV 401
            |....:|.|:::|:.:|..||.|
Worm   388 LNEKTFLRGVEIYETLINKLANV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6733	NP_651123.1	Ac-peptdase-euk	1..401	CDD:273850	178/411 (43%)
CG6733	NP_651123.1	M20_AcylaseI_like	8..399	CDD:193524	176/409 (43%)
C06A6.4	NP_001021301.1	M20_AcylaseI_like	3..408	CDD:349898	176/408 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160023
Domainoid	1	1.000	290	1.000	Domainoid score	I829
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110440
Inparanoid	1	1.050	332	1.000	Inparanoid score	I1424
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		mtm4767
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	O	PTHR45892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940