Protein Alignment CG6733 and PM20D1

DIOPT Version :9

• Sequence 1: NP_651123.1
• Gene: CG6733 / 42731
• FlyBaseID: FBgn0039052
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_689704.4
• Gene: PM20D1 / 148811
• HGNCID: 26518
• Length: 502
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 116/472 - (24%)
• Similarity: 183/472 - (38%)
• Gaps: 109/472 - (23%)

  Fly     8 NNEEIKIFREYLR----IPTV---HPDVDYTACVEFLKRQASSLNLPVEVVYPAVQTKPVV---- 61
            :.||....:|.|:    ||||   ....:.||..||.|.        :..|:|.|.:...:
Human    44 SKEERVAMKEALKGAIQIPTVTFSSEKSNTTALAEFGKY--------IHKVFPTVVSTSFIQHEV 100

  Fly    62 ------IIKWEGSQPELSSIVLNSHTDVVPVFREKWTHEPFSADIDEEGRIFARGTQDMKSVGTQ 120
                  :...:||.|.|...:|.:|.||||...|.|...|||. ::.:|.|:.|||.|.|:....
Human   101 VEEYSHLFTIQGSDPSLQPYLLMAHFDVVPAPEEGWEVPPFSG-LERDGIIYGRGTLDDKNSVMA 164

  Fly   121 YLGAIRLLKASGFKPKRNLYVTFVPDEETGGHLGMAEFVKTDYYKKMNAGFSLDEGATSESD--- 182
            .|.|:.||....:.|:|:.:::...|||:.| .|..........:.:...|.:|||.....|
Human   165 LLQALELLLIRKYIPRRSFFISLGHDEESSG-TGAQRISALLQSRGVQLAFIVDEGGFILDDFIP 228

  Fly   183 -----VHHLFYAERLRWGLKLKVSGTSGHGSLLLPNTAGVKLNYLVNKLTE------FRTSQV-- 234
                 :..:..:|:....|.|:|:.||||.|.....|:...|...|::|.:      |.:..|
Human   229 NFKKPIALIAVSEKGSMNLMLQVNMTSGHSSAPPKETSIGILAAAVSRLEQTPMPIIFGSGTVVT 293

  Fly   235 --ENLARD-------------------------SSLSKGDV-TTVNLTQLSGGVQSNVVPPLFEA 271
              :.||.:                         :.|:...: ||..||....||:.||:||:.:|
Human   294 VLQQLANEFPFPVNIILSNPWLFEPLISRFMERNPLTNAIIRTTTALTIFKAGVKFNVIPPVAQA 358

  Fly   272 VFDIRI----------AITVNVVAFEKQIRDWCEEAGGGIEIDF-----FQKEPYIGPTKLDNSN 321
            ..:.||          .:|.|:||..:              :.|     |...| :.|:. |.:.
Human   359 TVNFRIHPGQTVQEVLELTKNIVADNR--------------VQFHVLSAFDPLP-VSPSD-DKAL 407

  Fly   322 PYWL---AVKAAIDELGLKVHPIVCPGATDSRFIREKGTPAIGFSPII---NTTMRIHDHDEFLQ 380
            .|.|   .|::...|:.:.. |:...|.|||||.....|....|.||.   ....|||..:|.:.
Human   408 GYQLLRQTVQSVFPEVNITA-PVTSIGNTDSRFFTNLTTGIYRFYPIYIQPEDFKRIHGVNEKIS 471

  Fly   381 ADVYLNGIDVYKKIIRN 397
            ...|...:....::|:|
Human   472 VQAYETQVKFIFELIQN 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6733	NP_651123.1	Ac-peptdase-euk	1..401	CDD:273850	116/472 (25%)
		M20_AcylaseI_like	8..399	CDD:193524	116/472 (25%)
PM20D1	NP_689704.4	PRK08262	35..490	CDD:236208	116/472 (25%)
		M20_yscS	53..487	CDD:193549	112/460 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3343
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.800