Protein Alignment CG6726 and CNDP2

DIOPT Version :10

• Sequence 1: NP_651120.1
• Gene: CG6726 / 42728
• FlyBaseID: FBgn0039049
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_060705.2
• Gene: CNDP2 / 55748
• HGNCID: 24437
• Length: 475
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 97/484 - (20%)
• Similarity: 172/484 - (35%)
• Gaps: 141/484 - (29%)

  Fly     4 AKW----------ENNEEIKIFREYLRIPTVHPNVDYTVCTEFLKRQAASLDLPVEVIYPVNEQN 58
            |||          |...||:...|              |....:|:...|::|     ..:.:|.
Human    23 AKWVAIQSVSAWPEKRGEIRRMME--------------VAAADVKQLGGSVEL-----VDIGKQK 68

  Fly    59 ---------PVVVLKWQGSQPELPSIILNSHTDVVP-VFEEKWTHGPFSADLDAEGRIFARGSQD 113
                     |.::|...||.|:..::.:..|.||.| ..|:.|...||:. ::.:|:::.|||.|
Human    69 LPDGSEIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTL-VERDGKLYGRGSTD 132

  Fly   114 MKCVGTQYLGAVRALKASGYQPKRTIYLTYVPDEEVGGHLGMRELV---KSDYFKKLN---VGFS 172
            .|.....::.|:.|.:.:|.:....:.......||.|.. |:.||:   |..:||.::   :..:
Human   133 DKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSE-GLDELIFARKDTFFKDVDYVCISDN 196

  Fly   173 FDEGISSADETYAL----YY---AERTLWHLRFKISGTAGH-----------------GSLLLPN 213
            :..|......||.|    |:   .|.:...|...:.|.:.|                 |::|:|.
Human   197 YWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPG 261

  Fly   214 TAGEKLNYVVGKMMEFRKSQVQKLADDSSLEIGDVT------------------------TVNLT 254
                 :|..|..:.|    :..||.||...:|.:..                        :::|.
Human   262 -----INEAVAAVTE----EEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLH 317

  Fly   255 QLRGGVQSN----VVPPLLEAVFDIRIAVTVDIPAFEKQIRDWCEEAGGGIELEFEMK------- 308
            .:.|....:    |:|..:...|.||:...:......:|:..:..:....:....|.|
Human   318 GIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEFKVYMGHGG 382

  Fly   309 NPFVEPTKIDSSNAYWLAFKKALDDLGLKTRVRVFPGATDSRYIRYAG-IP-ALGFSPINNTPIL 371
            .|:|.    |.|:.::||.::|     :||...|.|..|     |..| || .|.|.......::
Human   383 KPWVS----DFSHPHYLAGRRA-----MKTVFGVEPDLT-----REGGSIPVTLTFQEATGKNVM 433

  Fly   372 L----------HDHDEFLKADTYLHGIEV 390
            |          |..:|.|....|:.|.::
Human   434 LLPVGSADDGAHSQNEKLNRYNYIEGTKM 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6726	NP_651120.1	M20_AcylaseI_like	8..399	CDD:349898	93/470 (20%)
CNDP2	NP_060705.2	M20_dipept_like_CNDP	7..473	CDD:349925	97/484 (20%)