DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17111 and CG15020

DIOPT Version :9

Sequence 1:	NP_651119.2	Gene:	CG17111 / 42727	FlyBaseID:	FBgn0039048	Length:	792	Species:	Drosophila melanogaster
Sequence 2:	NP_647901.1	Gene:	CG15020 / 38544	FlyBaseID:	FBgn0035543	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	84/448 - (18%)
Similarity:	153/448 - (34%)	Gaps:	80/448 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 RVKCLDVRVFCTRDEMTIKYNPKDWFVGKIYAS--MHSKDCL-ARGSGNGSVLLTLQIGSEVKEN 405
            ||:.::..  |..|.|.|:......|.|.:|::  .:..||: ..|||.......:|:      |
  Fly   216 RVQHIEAE--CQDDYMKIRIGFNGSFSGLLYSAGYAYDPDCMYINGSGRDYYEFYIQL------N 272

  Fly   406 RCGILRAYEMTQEYQR---TFISALVVIQNNPNVQTQGDRLIKVGCIQS-NATTSLGVSVRDSSV 466
            |||.|....:.:|.::   .|:...|.:|.||.::.:.|...||.|... :...::.....|..|
  Fly   273 RCGTLGKNSLQEESRKNPTNFMWNTVTVQYNPLIEEEYDEHFKVTCEYGYDFWKTVTFPFLDVEV 337

  Fly   467 DSSEPVPSAIALESSLEYTEHMFPHEGVVHYNSSTGPHPHPSISLQILDLSHQHETNDVQIGQNL 531
            .:..||...::            |.|..:...:..|             :.....|..|::|..|
  Fly   338 ATGNPVVFTLS------------PPECYMEIQNGYG-------------IGGPRVTGPVRVGDPL 377

  Fly   532 ELQIVAEYSPQQLAEHMELQLAPLPDFRATSLVAKTADNENFVLLIDERGCPTDASVFPALERVH 596
            .|.|           :|..:.... |.......|....|:. :.|||:.|||.|..:........
  Fly   378 TLII-----------YMRSKYDGF-DIVVNDCYAHNGANKR-IQLIDQHGCPVDDKLISRFRGSW 429

  Fly   597 TAS---RSMLRARFHAFKFSGTANVSFDVKIRFCVERCSPSNCISSSWQRRRRQADQPDRRPEDL 658
            :.|   .:.:.|....|:|:|:..:..:..:|.|..||....|   .|:..:....:........
  Fly   430 SDSGVYETQVYAYMKTFRFTGSPALYIECDVRMCHGRCPSQPC---HWRNLKAVTKRDTSNMTAT 491

  Fly   659 RVQNPVYISTVVDVAPQPDNFTRSQEELPLNYNIRVHGPDQSNTNSYLYGERGVLLIAGIDDPLH 723
            .:..|...:....:..:........|.:.|..::||....:::.:. :|..|..       .||.
  Fly   492 NISIPPLSADGEGLTTESPTANSLSENVNLFQSLRVLQEGETDGDD-VYAHRQT-------KPLS 548

  Fly   724 LDNVCINQSLLIAL----FIFWLICQVALLFGCGMVLQRYRRLAKLEDERRRLHEEYL 777
            ....|:..|...||    .....:..|.|...|..:.:|         :...|::.|:
  Fly   549 PHQTCLKTSTFSALTAGCSAVLCVLTVTLFIACSRLKRR---------KESSLYDSYI 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17111	NP_651119.2	PAN_1	159..255	CDD:278453
CG17111	NP_651119.2	PAN_AP_HGF	270..344	CDD:238532	84/448 (19%)
CG15020	NP_647901.1	ZP	223..473	CDD:214579	62/298 (21%)
CG15020	NP_647901.1	Zona_pellucida	<371..472	CDD:278526	25/113 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840