Protein Alignment CG17111 and noah-2

DIOPT Version :10

• Sequence 1: NP_651119.2
• Gene: CG17111 / 42727
• FlyBaseID: FBgn0039048
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_502699.1
• Gene: noah-2 / 178365
• WormBaseID: WBGene00009926
• Length: 741
• Species: Caenorhabditis elegans
• Alignment Length: 845
• Identity: 174/845 - (20%)
• Similarity: 299/845 - (35%)
• Gaps: 250/845 - (29%)

  Fly    21 ILLILQLNASVALLLKCPLHQLQLQKIVGF-RPPLEYLNADNRIYGPEMVSNFKTRNGQQELPVS 84
            |.|:|.:..:...:.:|..|:     ...| |.|...|:..     |.::|     ....:|..:
 Worm     5 IFLLLSIVPAAQSVFECSSHE-----TTAFVRIPRARLDGT-----PVVIS-----TAGHDLTCA 54

  Fly    85 QVCWRICNEDPDCIAYVHLLDTDECHGYSYFERTSRYL-----AISGELPLVADGEA--VFYEKT 142
            |.|..  |.:|...|      ...|..:::..|.:.|.     ..:|...|.|:..|  .:||||
 Worm    55 QYCRN--NIEPTTGA------QRVCASFNFDGRETCYFFDDAATPAGTSQLTANPSANNFYYEKT 111

  Fly   143 CL---RVPDACRGRLWALTKIPGSTLVYHSKKTISTLVTRRECAERCFFETQFRCLSASF----- 199
            |:   ...:||..|.::..:...:.|....||:: |:..|..|...|..|.:|.|.|.:|
 Worm   112 CIPNVSAHEACTYRSFSFERARNTQLEGFVKKSV-TVENREHCLSACLKEKEFVCKSVNFHYDTS 175

  Fly   200 -----------APS----------YRNNRERFRGEAGPG-------------------------- 217
                       .|:          |.||....:...||.
 Worm   176 LCELSVEDKRSKPTHVRMSEKIDYYDNNCLSRQNRCGPSGGNLVFVKTTNFEIRYYDHTQSVEAQ 240

  Fly   218 -----QRP-------------SPRLGRCMLSDRDKTVQPDAFRAAPYDEEYMENQCHERAIESDN 264
                 |:.             :|:...|::||.|...:.|. :.....::|.|..|....:.|..
 Worm   241 ESYCLQKCLDSLNTFCRSVEFNPKEKNCIVSDEDTFSRADQ-QGQVVGKDYYEPICVAADLSSST 304

  Fly   265 C----SYELYANSSF---IYAEARYLGLSQKECQAMCSHEAKFYCQGVSFYYVNQLSLSECLLHS 322
            |    ::|.:..||.   :.|.|:  |::..:|.::|.....  |:.:::    ..:.|.|.::
 Worm   305 CRQQAAFERFIGSSIEGEVVASAQ--GVTISDCISLCFQNLN--CKSINY----DRTASSCFIY- 360

  Fly   323 EDIVSLGPRSLKLREN-SVYMRRVKC---LDVRVFCTRDEMTIKYNPKDWFVGKIYASMHSKDCL 383
                ::|.:...::.| |:......|   ......||.:.:....|.|:.:.|.|||:.....|
 Worm   361 ----AVGRQDANIKANPSMDYYEFNCESQFGGMALCTNEGIRFIVNTKEPYTGAIYAAERFSTC- 420

  Fly   384 ARGSGNGSVLLTLQIGSEVKENR---------------CG-ILRAYEMTQEYQRTFISALVVIQN 432
                            |:|.||.               || ::|..:|         .||||:..
 Worm   421 ----------------SQVVENAKQISITFPPPTVSSDCGTVIRDGKM---------EALVVVSL 460

  Fly   433 N---PN-VQTQGDRLIKVGCIQSNATTSLGVSVRDSSVDSSEPVPSAIALESSLEYTEHMFPHEG 493
            :   |: |.|:.||..:|.|     ..|:...|::.||     |.:.| .|:|.:.|..:
 Worm   461 DGVLPHQVTTEWDRFYRVSC-----DVSMDKMVKEGSV-----VVTTI-YEASSQNTTVL----- 509

  Fly   494 VVHYNSSTGPHPHPSISLQILDLSHQHETNDVQIGQNLELQIVAEYSPQQLAEHMELQLAPLPDF 558
                  .....|..|..||||: ..:...:...||..|.|.|.:|    |...|..:    :.:.
 Worm   510 ------DVATPPPVSAELQILN-QLEEPLHKASIGDPLLLVITSE----QAGPHNMM----VTEC 559

  Fly   559 RATSLVAKTADNENFVLLIDERGCPTDASVFPALERVHTASRSMLRARFHAFKFSGTANVSFDVK 623
            .||. |....|...|.|:  |.|||...::...:|:....:|  |::...||:..|:.:|.....
 Worm   560 TATR-VGGFGDTVPFTLI--ENGCPRYPALVGPVEQDFDKNR--LKSDLRAFRLDGSYDVQIVCS 619

  Fly   624 IRFCV--ERCSPSNCISS-------SWQRRRRQADQPDRRPEDLRVQNPVYISTVVDVAPQPDNF 679
            |.||.  ..|..|||:.|       |..|::|.||......|:       .:|.::.|..:.::
 Worm   620 IMFCAGPNGCPVSNCLDSGTNELFMSHGRKKRSADLEAGETEE-------KLSAIIRVFAKGED- 676

  Fly   680 TRSQEELPLNYNIRVHGPDQSNTNSYLYGERGVLLIAGIDDPLHLDNV------CINQSLLIALF 738
               :||:.:..|..:.....|..         :|.||   :|..:.:|      |...|.:||::
 Worm   677 ---EEEMEMANNTMMTSMSDSTE---------LLCIA---EPFFVSSVVSLSVLCFALSAIIAIW 726

  Fly   739  738
             Worm   727  726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17111	NP_651119.2	PAN_1	159..255	CDD:459635	27/165 (16%)
		PAN_AP_HGF	270..344	CDD:238532	13/77 (17%)
		ZP	<566..627	CDD:214579	15/60 (25%)
noah-2	NP_502699.1	PAN_1	28..112	CDD:459635	22/101 (22%)
		PAN_AP_HGF	125..203	CDD:238532	15/78 (19%)
		PAN_AP_HGF	217..292	CDD:238532	8/75 (11%)
		PAN_1	310..382	CDD:459635	14/84 (17%)
		ZP	392..634	CDD:214579	73/303 (24%)