Protein Alignment CG17111 and let-653

DIOPT Version :10

• Sequence 1: NP_651119.2
• Gene: CG17111 / 42727
• FlyBaseID: FBgn0039048
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_001021336.2
• Gene: let-653 / 178120
• WormBaseID: WBGene00002827
• Length: 812
• Species: Caenorhabditis elegans
• Alignment Length: 931
• Identity: 185/931 - (19%)
• Similarity: 269/931 - (28%)
• Gaps: 342/931 - (36%)

  Fly     3 PLQSLVTAPRLCKLAIAAILLILQLNASVALLLKCPLHQLQLQKIVGFRPPLEYLNADNRIY--G 65
            ||.||:            :|:.....:|.|.:.||                       |..|  .
 Worm     4 PLISLL------------LLIAFYSTSSEAFVPKC-----------------------NSFYVRW 33

  Fly    66 PEMVSNFKTRNGQQELPVS-QVCWRICN--EDP-------DCIAYVHLLDTDECHGYSY------ 114
            |.:..|||   ...|..:| :.|...|:  |||       :|.|..|....|   |:|:
 Worm    34 PRVRLNFK---AVAEARLSLKGCQSACSLGEDPVSPGKQLECAAVNHQASPD---GFSHLCAVFQ 92

  Fly   115 ---FERTSRYLAISGELPLVADGEAVFYEKTCLRVPDACRGRLWALTKIPGSTLVYHSKKTI--- 173
               .:....|:.        ||....||.|.||.....|.|. :|.|.:...   |..:|::
 Worm    93 PHQLQNVDGYVE--------ADDRFTFYWKYCLPSTRKCSGE-YAFTYLSDR---YMDQKSVIKW 145

  Fly   174 STLVTRRECAERCFFETQFRCLSASFAPSYRNNRERFRGEAGPGQRPSPRLGRCMLSDRDKTVQP 238
            :|.....||...|..|..|.|.|.||      ||..               |.|.:|...:..:|
 Worm   146 TTKANLEECLSDCLDEKSFECRSISF------NRTD---------------GGCHMSKDSQISRP 189

  Fly   239 DAFRA---APYDEEYMENQCHERAIESDNCSYELYANSSFIYAEAR--YLGLSQKECQAM----- 293
            :|.|.   ..|..:|.||.|:..: ||....:|...|...:..::|  |.|       |:
 Worm   190 EAIRLNNNPNYRIDYYENNCYNLS-ESFTFKHECRDNGISVSVKSRLPYTG-------AIYGLYD 246

  Fly   294 ---CSHEAKFYCQGVSF--YYVNQLSLSECLLHSEDIVSLGPRSLKLRENSVYMRRVKCLD---V 350
               |..|.|   :...|  ::..|.....|           ..|:|.:.|.:.:..|...|   .
 Worm   247 FFTCRTEPK---EATEFDHFFPYQTVSKNC-----------SDSIKYKGNEMVLEVVLSTDGIEP 297

  Fly   351 RVFCTRDEMTIKYNPKDWFVG--------------------KIYASMHSKDCLARGSGNGSVL-- 393
            ..|.|.:::|  |..|....|                    .:.||.|:...|...:|:...|
 Worm   298 LYFITPEDLT--YQAKCPISGVKAKDPANTKSSAHLDNRNKAMEASAHALFELLSKTGDDEALQN 360

  Fly   394 ---LTLQIGSEV-----------------KENRCGILRAYEMTQEYQRTFISALVVIQN------ 432
               |.|...:||                 |:.........:.:|:...|...:.|||..
 Worm   361 TFPLPLTTTTEVIRQVTTTTKKPSTTTSTKKLTTTTTTTPKPSQKPTTTTTKSPVVITTTTKTSP 425

  Fly   433 ----------------------------NPNVQTQGDRLIKVGCI-------------------- 449
                                        ||...|......||..|
 Worm   426 KPTTSPSTTTSTTTSTTIPPSTTTRKPANPRRSTIMSATSKVAIIVGKDSSFARARLFTTKHPST 490

  Fly   450 -----------------------------------QSNATTSLGVSV----RDSSVDSSEPVPSA 475
                                               ...||||...:.    :.::|.|:..:||.
 Worm   491 QKIDVPTTTVQTSTTVPTTPSKTTATTTTTPKPTTTETATTSSSTTTVTTQKPTTVTSTTTLPST 555

  Fly   476 IALESSLEYTEHMFP--------HEG--------VVHYNSSTGPHPHPSISLQILDLSHQHE-TN 523
            .|  |:...|....|        |.|        |.|..|:....|...:   |.|:.|..: ..
 Worm   556 TA--STTTKTTTSTPTSPQTTTTHVGAPASSVASVAHDGSTLAGKPKVPV---IFDIFHNGQPVE 615

  Fly   524 DVQIGQNLELQIVAEYS-PQQLAEHMELQLAPL-PDFRATSLVAKTADNENFVLLIDERGCPTD- 585
            .|.:|..:.|.....|. |.:..:....|:.|: |.:          :.|:..|.|...|||.|
 Worm   616 AVVVGTKISLSFRPHYPIPPEYVDVRGCQVEPIDPKY----------EWEHEPLFIIRDGCPADG 670

  Fly   586 -ASVFPALERVHTASRSMLRARFHAFKFSGTANVSFDVKIRFCVERCSPSN-------CISSSWQ 642
             ..|.|.     |.|....:....||::..|..|.:...:|.|.....|.|       |.||...
 Worm   671 VGLVCPP-----THSEFGAKVSVEAFRYQTTGQVQYSCLVRICPFAPCPKNTCDDVEGCDSSYMH 730

  Fly   643 RRRRQADQPD------RRPEDLRVQNPVYISTVVDVAPQPDNFTRSQEELPLNYNIRVHGPDQSN 701
            |.||:....|      ..|| |..|..:..|.......:..|||...||   ...|.:.|
 Worm   731 RYRRELSLEDIKKALEANPE-LASQFGISPSAFARNPSKSKNFTSVVEE---QQRIALGG----- 786

  Fly   702 TNSYLYGERGVLLIAGIDDPL 722
              .||...|  |::...:|.|
 Worm   787 --DYLVRRR--LIVVNSEDQL 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17111	NP_651119.2	PAN_1	159..255	CDD:459635	24/101 (24%)
		PAN_AP_HGF	270..344	CDD:238532	14/85 (16%)
		ZP	<566..627	CDD:214579	16/62 (26%)
let-653	NP_001021336.2	PAN_AP_HGF	124..208	CDD:238532	26/108 (24%)
		ZP	<606..727	CDD:214579	30/135 (22%)